2nq8: Difference between revisions

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==Malarial enoyl acyl ACP reductase bound with INH-NAD adduct==
==Malarial enoyl acyl ACP reductase bound with INH-NAD adduct==
<StructureSection load='2nq8' size='340' side='right' caption='[[2nq8]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2nq8' size='340' side='right'caption='[[2nq8]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2nq8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NQ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NQ8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2nq8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NQ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NQ8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZID:ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE+DINUCLEOTIDE'>ZID</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FabI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZID:ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE+DINUCLEOTIDE'>ZID</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2nq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nq8 OCA], [http://pdbe.org/2nq8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2nq8 RCSB], [http://www.ebi.ac.uk/pdbsum/2nq8 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nq8 OCA], [https://pdbe.org/2nq8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nq8 RCSB], [https://www.ebi.ac.uk/pdbsum/2nq8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nq8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9BJJ9_PLAFA Q9BJJ9_PLAFA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nq/2nq8_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nq/2nq8_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
*[[Enoyl-Acyl-Carrier Protein Reductase|Enoyl-Acyl-Carrier Protein Reductase]]
*[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Plafa]]
[[Category: Large Structures]]
[[Category: Fidock, D A]]
[[Category: Plasmodium falciparum]]
[[Category: Freundlich, J S]]
[[Category: Fidock DA]]
[[Category: Jacobs, W R]]
[[Category: Freundlich JS]]
[[Category: Jacobus, D P]]
[[Category: Jacobs Jr WR]]
[[Category: Karagyozov, L]]
[[Category: Jacobus DP]]
[[Category: Kuo, M]]
[[Category: Karagyozov L]]
[[Category: Lucumi, E]]
[[Category: Kuo M]]
[[Category: Sacchettini, J C]]
[[Category: Lucumi E]]
[[Category: Schiehser, G A]]
[[Category: Sacchettini JC]]
[[Category: Tsai, H C]]
[[Category: Schiehser GA]]
[[Category: Valderramos, J C]]
[[Category: Tsai HC]]
[[Category: Yu, M]]
[[Category: Valderramos JC]]
[[Category: Inh]]
[[Category: Yu M]]
[[Category: Malaria]]
[[Category: Oxidoreductase]]
[[Category: Pfenr]]

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