3hxp: Difference between revisions

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==Crystal structure of the FhuD fold-family BSU3320, a periplasmic binding protein component of a Fep/Fec-like ferrichrome ABC transporter from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR577==
==Crystal structure of the FhuD fold-family BSU3320, a periplasmic binding protein component of a Fep/Fec-like ferrichrome ABC transporter from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR577==
<StructureSection load='3hxp' size='340' side='right' caption='[[3hxp]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
<StructureSection load='3hxp' size='340' side='right'caption='[[3hxp]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3hxp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HXP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HXP FirstGlance]. <br>
<table><tr><td colspan='2'>[[3hxp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HXP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HXP FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3g9q|3g9q]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BSU33320, fhuD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Bacillus globigii" Migula 1900])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hxp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hxp OCA], [https://pdbe.org/3hxp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hxp RCSB], [https://www.ebi.ac.uk/pdbsum/3hxp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hxp ProSAT], [https://www.topsan.org/Proteins/NESGC/3hxp TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hxp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hxp OCA], [http://pdbe.org/3hxp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hxp RCSB], [http://www.ebi.ac.uk/pdbsum/3hxp PDBsum], [http://www.topsan.org/Proteins/NESGC/3hxp TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FHUD_BACSU FHUD_BACSU]] Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of ferrichrome and coprogen.<ref>PMID:8388528</ref> <ref>PMID:16672620</ref>
[https://www.uniprot.org/uniprot/FHUD_BACSU FHUD_BACSU] Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of ferrichrome and coprogen.<ref>PMID:8388528</ref> <ref>PMID:16672620</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/3hxp_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/3hxp_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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==See Also==
==See Also==
*[[ABC transporter|ABC transporter]]
*[[ABC transporter 3D structures|ABC transporter 3D structures]]
*[[Ferric hydroxamate uptake receptor|Ferric hydroxamate uptake receptor]]
*[[Ferric hydroxamate uptake receptor|Ferric hydroxamate uptake receptor]]
== References ==
== References ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus globigii migula 1900]]
[[Category: Bacillus subtilis]]
[[Category: Acton, T B]]
[[Category: Large Structures]]
[[Category: Chen,C X]]
[[Category: Acton TB]]
[[Category: Cunningham,K]]
[[Category: Chen CX]]
[[Category: Everett, J K]]
[[Category: Cunningham K]]
[[Category: Fang,F]]
[[Category: Everett JK]]
[[Category: Forouhar,F]]
[[Category: Fang F]]
[[Category: Hunt,J F]]
[[Category: Forouhar F]]
[[Category: Ma,L]]
[[Category: Hunt JF]]
[[Category: Montelione, G T]]
[[Category: Ma L]]
[[Category: Structural genomic]]
[[Category: Montelione GT]]
[[Category: Nair, R]]
[[Category: Nair R]]
[[Category: Neely, H]]
[[Category: Neely H]]
[[Category: Rost, B]]
[[Category: Rost B]]
[[Category: Seetharaman, J]]
[[Category: Seetharaman J]]
[[Category: Tong,L]]
[[Category: Tong L]]
[[Category: Xiao,R]]
[[Category: Xiao R]]
[[Category: Alpha-beta protein]]
[[Category: Cell membrane]]
[[Category: Ion transport]]
[[Category: Iron]]
[[Category: Iron transport]]
[[Category: Lipoprotein]]
[[Category: Membrane]]
[[Category: Nesg]]
[[Category: Palmitate]]
[[Category: PSI, Protein structure initiative]]
[[Category: Transport]]
[[Category: Transport protein]]

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