1s96: Difference between revisions

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==The 2.0 A X-ray structure of Guanylate Kinase from E.coli==
==The 2.0 A X-ray structure of Guanylate Kinase from E.coli==
<StructureSection load='1s96' size='340' side='right' caption='[[1s96]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='1s96' size='340' side='right'caption='[[1s96]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1s96]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S96 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1S96 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1s96]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S96 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S96 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GMK, SPOR, B3648, C4473, SF3688, S4081 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s96 OCA], [https://pdbe.org/1s96 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s96 RCSB], [https://www.ebi.ac.uk/pdbsum/1s96 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s96 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Guanylate_kinase Guanylate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.8 2.7.4.8] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1s96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s96 OCA], [http://pdbe.org/1s96 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1s96 RCSB], [http://www.ebi.ac.uk/pdbsum/1s96 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/KGUA_ECOLI KGUA_ECOLI]] Essential for recycling GMP and indirectly, cGMP.<ref>PMID:8390989</ref>
[https://www.uniprot.org/uniprot/KGUA_ECOLI KGUA_ECOLI] Essential for recycling GMP and indirectly, cGMP.<ref>PMID:8390989</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s9/1s96_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s9/1s96_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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==See Also==
==See Also==
*[[Guanylate kinase|Guanylate kinase]]
*[[Guanylate kinase 3D structures|Guanylate kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Guanylate kinase]]
[[Category: Large Structures]]
[[Category: Klock, H E]]
[[Category: Klock HE]]
[[Category: Kreusch, A]]
[[Category: Kreusch A]]
[[Category: Lesley, S A]]
[[Category: Lesley SA]]
[[Category: McMullan, D]]
[[Category: McMullan D]]
[[Category: Rodrigues, K]]
[[Category: Rodrigues K]]
[[Category: Spraggon, G]]
[[Category: Spraggon G]]
[[Category: Vincent, J]]
[[Category: Vincent J]]
[[Category: Dimer]]
[[Category: E coli]]
[[Category: Sad]]
[[Category: Transferase]]

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