2vdu: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-==STRUCTURE OF TRM8-TRM82, THE YEAST TRNA M7G METHYLATION COMPLEX==
-<StructureSection load='2vdu' size='340' side='right' caption='[[2vdu]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+==Structure of trm8-trm82, THE YEAST TRNA m7G methylation complex==
+<StructureSection load='2vdu' size='340' side='right'caption='[[2vdu]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2vdu]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VDU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VDU FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2vdu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VDU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VDU FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2vdv|2vdv]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(46)-N(7))-methyltransferase tRNA (guanine(46)-N(7))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.33 2.1.1.33] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vdu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vdu OCA], [https://pdbe.org/2vdu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vdu RCSB], [https://www.ebi.ac.uk/pdbsum/2vdu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vdu ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vdu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vdu OCA], [http://pdbe.org/2vdu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vdu RCSB], [http://www.ebi.ac.uk/pdbsum/2vdu PDBsum]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/TRM82_YEAST TRM82_YEAST]] Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA, a modification required to maintain stability of tRNAs; its absence resulting in tRNA decay. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.<ref>PMID:15811913</ref> <ref>PMID:16387656</ref> <ref>PMID:17382321</ref> <ref>PMID:18184583</ref>  [[http://www.uniprot.org/uniprot/TRMB_YEAST TRMB_YEAST]] Methyltransferase that catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA, a modification required to maintain stability of tRNAs; its absence resulting in tRNA decay. Both the D-stem and T-stem structures of tRNAs are required for efficient methyltransferase activity.[HAMAP-Rule:MF_03055]<ref>PMID:16387656</ref> <ref>PMID:17382321</ref>
+[https://www.uniprot.org/uniprot/TRM82_YEAST TRM82_YEAST] Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA, a modification required to maintain stability of tRNAs; its absence resulting in tRNA decay. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.<ref>PMID:15811913</ref> <ref>PMID:16387656</ref> <ref>PMID:17382321</ref> <ref>PMID:18184583</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vd/2vdu_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vd/2vdu_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
@@ Line 31: / Line 31: @@
 ==See Also==
-*[[TRNA methyltransferase|TRNA methyltransferase]]
+*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Atcc 18824]]
+[[Category: Large Structures]]
-[[Category: Blondeau, K]]
+[[Category: Saccharomyces cerevisiae]]
-[[Category: Chaillet, M]]
+[[Category: Blondeau K]]
-[[Category: Durand, D]]
+[[Category: Chaillet M]]
-[[Category: Leulliot, N]]
+[[Category: Durand D]]
-[[Category: Tilbeurgh, H Van]]
+[[Category: Leulliot N]]
-[[Category: Ulryck, N]]
+[[Category: Ulryck N]]
-[[Category: M7g]]
+[[Category: Van Tilbeurgh H]]
-[[Category: Methyltransferase]]
-[[Category: Phosphorylation]]
-[[Category: S-adenosyl-l-methionine]]
-[[Category: Spout mt]]
-[[Category: Transferase]]
-[[Category: Trna]]
-[[Category: Trna processing]]
-[[Category: Wd repeat]]