1gm9: Difference between revisions

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 ==Crystal structures of penicillin acylase enzyme-substrate complexes: Structural insights into the catalytic mechanism==
-<StructureSection load='1gm9' size='340' side='right' caption='[[1gm9]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
+<StructureSection load='1gm9' size='340' side='right'caption='[[1gm9]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1gm9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GM9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GM9 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1gm9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GM9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GM9 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SOX:N-[(2S,4S,6R)-2-(DIHYDROXYMETHYL)-4-HYDROXY-3,3-DIMETHYL-7-OXO-4LAMBDA~4~-THIA-1-AZABICYCLO[3.2.0]HEPT-6-YL]-2-PHENYLACETAMIDE'>SOX</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SME:METHIONINE+SULFOXIDE'>SME</scene></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SME:METHIONINE+SULFOXIDE'>SME</scene>, <scene name='pdbligand=SOX:N-[(2S,4S,6R)-2-(DIHYDROXYMETHYL)-4-HYDROXY-3,3-DIMETHYL-7-OXO-4LAMBDA~4~-THIA-1-AZABICYCLO[3.2.0]HEPT-6-YL]-2-PHENYLACETAMIDE'>SOX</scene></td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ai4|1ai4]], [[1ai5|1ai5]], [[1ai6|1ai6]], [[1ai7|1ai7]], [[1ajn|1ajn]], [[1ajp|1ajp]], [[1ajq|1ajq]], [[1cp9|1cp9]], [[1e3a|1e3a]], [[1fxh|1fxh]], [[1fxv|1fxv]], [[1gk9|1gk9]], [[1gkf|1gkf]], [[1gm7|1gm7]], [[1gm8|1gm8]], [[1pnk|1pnk]], [[1pnl|1pnl]], [[1pnm|1pnm]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gm9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gm9 OCA], [https://pdbe.org/1gm9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gm9 RCSB], [https://www.ebi.ac.uk/pdbsum/1gm9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gm9 ProSAT]</span></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PAC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gm9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gm9 OCA], [http://pdbe.org/1gm9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gm9 RCSB], [http://www.ebi.ac.uk/pdbsum/1gm9 PDBsum]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/PAC_ECOLX PAC_ECOLX]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gm/1gm9_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gm/1gm9_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
@@ Line 36: / Line 36: @@
 __TOC__
 </StructureSection>
-[[Category: Bacillus coli migula 1895]]
+[[Category: Escherichia coli]]
-[[Category: Penicillin amidase]]
+[[Category: Large Structures]]
-[[Category: Brannigan, J A]]
+[[Category: Brannigan JA]]
-[[Category: Dodson, G G]]
+[[Category: Dodson GG]]
-[[Category: McVey, C E]]
+[[Category: McVey CE]]
-[[Category: Walsh, M A]]
+[[Category: Walsh MA]]
-[[Category: Wilson, K S]]
+[[Category: Wilson KS]]
-[[Category: Antibiotic resistance]]
-[[Category: Hydrolase]]