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==Solution structure of the C2H2 type zinc finger (region 368-400) of human Zinc finger protein 347==
==Solution structure of the C2H2 type zinc finger (region 368-400) of human Zinc finger protein 347==
<StructureSection load='2eow' size='340' side='right' caption='[[2eow]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2eow' size='340' side='right'caption='[[2eow]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2eow]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EOW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EOW FirstGlance]. <br>
<table><tr><td colspan='2'>[[2eow]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EOW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EOW FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZNF347 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eow OCA], [http://pdbe.org/2eow PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2eow RCSB], [http://www.ebi.ac.uk/pdbsum/2eow PDBsum], [http://www.topsan.org/Proteins/RSGI/2eow TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eow OCA], [https://pdbe.org/2eow PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eow RCSB], [https://www.ebi.ac.uk/pdbsum/2eow PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eow ProSAT], [https://www.topsan.org/Proteins/RSGI/2eow TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ZN347_HUMAN ZN347_HUMAN]] May be involved in transcriptional regulation.  
[https://www.uniprot.org/uniprot/ZN347_HUMAN ZN347_HUMAN] May be involved in transcriptional regulation.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eo/2eow_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eo/2eow_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Abe, H]]
[[Category: Large Structures]]
[[Category: Kigawa, T]]
[[Category: Abe H]]
[[Category: Kobayashi, N]]
[[Category: Kigawa T]]
[[Category: Koshiba, S]]
[[Category: Kobayashi N]]
[[Category: Li, H]]
[[Category: Koshiba S]]
[[Category: Structural genomic]]
[[Category: Li H]]
[[Category: Saito, K]]
[[Category: Saito K]]
[[Category: Sato, M]]
[[Category: Sato M]]
[[Category: Tochio, N]]
[[Category: Tochio N]]
[[Category: Tomizawa, T]]
[[Category: Tomizawa T]]
[[Category: Yokoyama, S]]
[[Category: Yokoyama S]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Rsgi]]
[[Category: Transcription]]
[[Category: Zf-c2h2]]

Latest revision as of 21:53, 29 May 2024

Solution structure of the C2H2 type zinc finger (region 368-400) of human Zinc finger protein 347Solution structure of the C2H2 type zinc finger (region 368-400) of human Zinc finger protein 347

Structural highlights

2eow is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

ZN347_HUMAN May be involved in transcriptional regulation.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Drag the structure with the mouse to rotate

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OCA
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