3f2g: Difference between revisions
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==Crystal structure of MerB mutant C160S, the Organomercurial Lyase involved in a bacterial mercury resistance system== | ==Crystal structure of MerB mutant C160S, the Organomercurial Lyase involved in a bacterial mercury resistance system== | ||
<StructureSection load='3f2g' size='340' side='right' caption='[[3f2g]], [[Resolution|resolution]] 1.78Å' scene=''> | <StructureSection load='3f2g' size='340' side='right'caption='[[3f2g]], [[Resolution|resolution]] 1.78Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3f2g]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3f2g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F2G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F2G FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.781Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f2g OCA], [https://pdbe.org/3f2g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f2g RCSB], [https://www.ebi.ac.uk/pdbsum/3f2g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f2g ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/MERB_ECOLX MERB_ECOLX] Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f2/3f2g_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f2/3f2g_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Di Lello P]] | ||
[[Category: | [[Category: Lafrance-Vanasse J]] | ||
[[Category: | [[Category: Lefebvre M]] | ||
[[Category: Omichinski | [[Category: Omichinski JG]] | ||
[[Category: Sygusch | [[Category: Sygusch J]] | ||