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==Crystal Structure of Iridoid Synthase from Cantharanthus roseus in complex with NAD+ and 10-oxogeranial==
==Crystal Structure of Iridoid Synthase from Cantharanthus roseus in complex with NAD+ and 10-oxogeranial==
<StructureSection load='5dbi' size='340' side='right' caption='[[5dbi]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='5dbi' size='340' side='right'caption='[[5dbi]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5dbi]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DBI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DBI FirstGlance]. <br>
<table><tr><td colspan='2'>[[5dbi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Catharanthus_roseus Catharanthus roseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DBI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DBI FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=XOG:(2E,6E)-2,6-DIMETHYLOCTA-2,6-DIENEDIAL'>XOG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dbf|5dbf]], [[5dbg|5dbg]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=XOG:(2E,6E)-2,6-DIMETHYLOCTA-2,6-DIENEDIAL'>XOG</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Iridoid_synthase Iridoid synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.99 1.3.1.99] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dbi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dbi OCA], [https://pdbe.org/5dbi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dbi RCSB], [https://www.ebi.ac.uk/pdbsum/5dbi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dbi ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dbi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dbi OCA], [http://pdbe.org/5dbi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dbi RCSB], [http://www.ebi.ac.uk/pdbsum/5dbi PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IRIS_CATRO IRIS_CATRO]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Iridoid synthase]]
[[Category: Catharanthus roseus]]
[[Category: Chen, C C]]
[[Category: Large Structures]]
[[Category: Guo, R T]]
[[Category: Chen CC]]
[[Category: Hu, Y M]]
[[Category: Guo RT]]
[[Category: Ko, T P]]
[[Category: Hu YM]]
[[Category: Liu, W D]]
[[Category: Ko TP]]
[[Category: Xu, Z X]]
[[Category: Liu WD]]
[[Category: Zheng, Y Y]]
[[Category: Xu ZX]]
[[Category: Acidocalcisomal pyrophosphatase]]
[[Category: Zheng YY]]
[[Category: Inhibitor]]
[[Category: Metal-binding]]
[[Category: Oxidoreductase]]
[[Category: Substrate binding]]

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