Beta2 adrenergic receptor-Gs protein complex: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
No edit summary |
||
| (3 intermediate revisions by 3 users not shown) | |||
| Line 1: | Line 1: | ||
<StructureSection load='3sn6' size='340' side='right' caption='Adrenergic receptor (blue) complex with G protein α subunit (grey), β subunit (green), γ-2 subunit (gold), antibody fragment (Orchid) and benzoxazin derivative [[3sn6]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
<StructureSection load=' | |||
==Introduction== | ==Introduction== | ||
[[G protein-coupled receptors]] (GPCRs) are a large family of protein receptors, which have seven-transmembrane helices and are found over a large array of eukaryotic cells. These receptors take a major part in a multitude of signal transduction pathways, including amongst others responses to hormones and neurotransmitters, sensing light, taste and smell, and many more. These receptors are also involved in many different types of diseases and are the target of almost 50% of current medical drugs. | [[G protein-coupled receptors]] (GPCRs) are a large family of protein receptors, which have seven-transmembrane helices and are found over a large array of eukaryotic cells. These receptors take a major part in a multitude of signal transduction pathways, including amongst others responses to hormones and neurotransmitters, sensing light, taste and smell, and many more. These receptors are also involved in many different types of diseases and are the target of almost 50% of current medical drugs. | ||
| Line 46: | Line 46: | ||
*[[User:Wayne Decatur/UNH BCHEM833 Structural Analysis Workshop Session Fall 2012|User:Wayne Decatur/UNH BCHEM833 Structural Analysis Workshop Session Fall 2012]] | *[[User:Wayne Decatur/UNH BCHEM833 Structural Analysis Workshop Session Fall 2012|User:Wayne Decatur/UNH BCHEM833 Structural Analysis Workshop Session Fall 2012]] | ||
*[[User:Wayne Decatur/UNH BCHEM833 Structural Proteomics Introductory Lecture Fall 2012|User:Wayne Decatur/UNH BCHEM833 Structural Proteomics Introductory Lecture Fall 2012]] | *[[User:Wayne Decatur/UNH BCHEM833 Structural Proteomics Introductory Lecture Fall 2012|User:Wayne Decatur/UNH BCHEM833 Structural Proteomics Introductory Lecture Fall 2012]] | ||
*[[ | *[[3sn6|3SN6]] | ||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||