5frt: Difference between revisions

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-'''Unreleased structure'''
-The entry 5frt is ON HOLD
+==Structure of the FeSII (shethna) protein of Azotobacter vinelandii==
+<StructureSection load='5frt' size='340' side='right'caption='[[5frt]], [[Resolution|resolution]] 2.34&Aring;' scene=''>
-Authors: Kabasakal, B.V., Cotton, C.A.R., Lieber, L., Murray, J.W.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5frt]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FRT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FRT FirstGlance]. <br>
-Description: Structure of the FeSII (shethna) protein of Azotobacter vinelandii
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.34&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>
-[[Category: Cotton, C.A.R]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5frt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5frt OCA], [https://pdbe.org/5frt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5frt RCSB], [https://www.ebi.ac.uk/pdbsum/5frt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5frt ProSAT]</span></td></tr>
-[[Category: Lieber, L]]
+</table>
-[[Category: Kabasakal, B.V]]
+== Function ==
-[[Category: Murray, J.W]]
+[https://www.uniprot.org/uniprot/FESII_AZOVI FESII_AZOVI] Binds to and protects nitrogenase from irreversible exposure to O(2), in what is known as 'conformational protection' (PubMed:7830548, PubMed:7548055, PubMed:10220344, PubMed:26654855). Shifts nitrogenase into an inactive, O(2)-tolerant state. Exists in 2 states, an open oxidized state that binds and protects nitrogenase, and a closed reduced state that probably does not bind nitrogenase; cooperative oxidation of the 2Fe-2S clusters causes the conformation change (PubMed:26654855). Does not protect nitrogenase with the vanadium-iron subunit, not clear if it protects the iron-only nitrogenase (PubMed:7830548).<ref>PMID:10220344</ref> <ref>PMID:26654855</ref> <ref>PMID:7548055</ref> <ref>PMID:7830548</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Azotobacter vinelandii]]
+[[Category: Large Structures]]
+[[Category: Cotton CAR]]
+[[Category: Kabasakal BV]]
+[[Category: Lieber L]]
+[[Category: Murray JW]]