5eqq: Difference between revisions
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New page: '''Unreleased structure''' The entry 5eqq is ON HOLD Authors: Soumana, D., Yilmaz, N.K., Ali, A., Prachanronarong, K.L., Aydin, C., Schiffer, C.A. Description: Crystal structure of HCV... |
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==Crystal structure of HCV NS3/4A WT protease in complex with 5172-Linear (MK-5172 linear analogue)== | |||
<StructureSection load='5eqq' size='340' side='right'caption='[[5eqq]], [[Resolution|resolution]] 1.65Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5eqq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_C Hepacivirus C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EQQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EQQ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5RS:~{tert}-butyl+~{N}-[(2~{S})-1-[(2~{S},4~{R})-2-[[(1~{R},2~{R})-1-(cyclopropylsulfonylcarbamoyl)-2-ethyl-cyclopropyl]carbamoyl]-4-(3-ethyl-7-methoxy-quinoxalin-2-yl)oxy-pyrrolidin-1-yl]-3,3-dimethyl-1-oxidanylidene-butan-2-yl]carbamate'>5RS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5eqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eqq OCA], [https://pdbe.org/5eqq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5eqq RCSB], [https://www.ebi.ac.uk/pdbsum/5eqq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5eqq ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/C1KIK8_9HEPC C1KIK8_9HEPC] | |||
==See Also== | |||
*[[Virus protease 3D structures|Virus protease 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Hepacivirus C]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Ali A]] | ||
[[Category: | [[Category: Aydin C]] | ||
[[Category: | [[Category: Prachanronarong KL]] | ||
[[Category: | [[Category: Schiffer CA]] | ||
[[Category: Soumana D]] | |||
[[Category: Yilmaz NK]] | |||
Latest revision as of 15:29, 6 March 2024
Crystal structure of HCV NS3/4A WT protease in complex with 5172-Linear (MK-5172 linear analogue)Crystal structure of HCV NS3/4A WT protease in complex with 5172-Linear (MK-5172 linear analogue)
Structural highlights
FunctionSee Also |
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