2rl1: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
New page: left|200px {{Structure |PDB= 2rl1 |SIZE=350|CAPTION= <scene name='initialview01'>2rl1</scene>, resolution 2.200Å |SITE= <scene name='pdbsite=AC1:So4+Binding+Site...
 
No edit summary
 
(11 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:2rl1.jpg|left|200px]]


{{Structure
==Crystal structure of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae in complex with UDP-N-acetylglucosamine==
|PDB= 2rl1 |SIZE=350|CAPTION= <scene name='initialview01'>2rl1</scene>, resolution 2.200&Aring;
<StructureSection load='2rl1' size='340' side='right'caption='[[2rl1]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+713'>AC1</scene> and <scene name='pdbsite=AC2:Ud1+Binding+Site+For+Residue+A+712'>AC2</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UD1:URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE'>UD1</scene>
<table><tr><td colspan='2'>[[2rl1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RL1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RL1 FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_1-carboxyvinyltransferase UDP-N-acetylglucosamine 1-carboxyvinyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.7 2.5.1.7] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
|GENE= MurZ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 Haemophilus influenzae])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UD1:URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE'>UD1</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK09369 PRK09369], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01555 UdpNAET]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rl1 OCA], [https://pdbe.org/2rl1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rl1 RCSB], [https://www.ebi.ac.uk/pdbsum/2rl1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rl1 ProSAT]</span></td></tr>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rl1 OCA], [http://www.ebi.ac.uk/pdbsum/2rl1 PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2rl1 RCSB]</span>
</table>
}}
== Function ==
[https://www.uniprot.org/uniprot/MURA_HAEIN MURA_HAEIN] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rl/2rl1_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rl1 ConSurf].
<div style="clear:both"></div>


'''Crystal structure of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae in complex with UDP-N-acetylglucosamine'''
==See Also==
 
*[[Enoylpyruvate transferase 3D structures|Enoylpyruvate transferase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2RL1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RL1 OCA].
 
==Reference==
Crystal structure of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae in complex with UDP-N-acetylglucosamine and fosfomycin., Yoon HJ, Lee SJ, Mikami B, Park HJ, Yoo J, Suh SW, Proteins. 2008 Feb 4;71(2):1032-1037. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18247346 18247346]
[[Category: Haemophilus influenzae]]
[[Category: Haemophilus influenzae]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: UDP-N-acetylglucosamine 1-carboxyvinyltransferase]]
[[Category: Suh SW]]
[[Category: Suh, S W.]]
[[Category: Yoon HJ]]
[[Category: Yoon, H J.]]
[[Category: cell cycle]]
[[Category: cell division]]
[[Category: cell shape]]
[[Category: cell wall biogenesis/degradation]]
[[Category: cytoplasm]]
[[Category: mura]]
[[Category: murz]]
[[Category: peptidoglycan synthesis]]
[[Category: transferase]]
[[Category: udp-n-acetylglucosamine]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 09:53:45 2008''

Latest revision as of 16:54, 13 March 2024

Crystal structure of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae in complex with UDP-N-acetylglucosamineCrystal structure of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae in complex with UDP-N-acetylglucosamine

Structural highlights

2rl1 is a 1 chain structure with sequence from Haemophilus influenzae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MURA_HAEIN Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2rl1, resolution 2.20Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=2rl1&oldid=4089147"