4ywc: Difference between revisions

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==Crystal structure of Myc3(5-242) fragment in complex with Jaz9(218-239) peptide==
==Crystal structure of Myc3(5-242) fragment in complex with Jaz9(218-239) peptide==
<StructureSection load='4ywc' size='340' side='right' caption='[[4ywc]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='4ywc' size='340' side='right'caption='[[4ywc]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ywc]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YWC FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ywc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YWC FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rru|4rru]], [[4rqw|4rqw]], [[4rs9|4rs9]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ywc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ywc OCA], [http://pdbe.org/4ywc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ywc RCSB], [http://www.ebi.ac.uk/pdbsum/4ywc PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ywc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ywc OCA], [https://pdbe.org/4ywc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ywc RCSB], [https://www.ebi.ac.uk/pdbsum/4ywc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ywc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MYC3_ARATH MYC3_ARATH]] Transcription factor involved in tryptophan, jasmonic acid (JA) and other stress-responsive gene regulation. With MYC2 and MYC4, controls additively subsets of JA-dependent responses. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the G-box (5'-CACGTG-3') of promoters. Activates multiple TIFY/JAZ promoters.<ref>PMID:12136026</ref> <ref>PMID:21242320</ref> <ref>PMID:21321051</ref> <ref>PMID:21335373</ref> <ref>PMID:23943862</ref> [[http://www.uniprot.org/uniprot/TIF7_ARATH TIF7_ARATH]] Repressor of jasmonate responses negatively regulated by the proteasome in an SCF(COI1) E3 ubiquitin-protein ligase complex-dependent manner. Jasmonoyl-isoleucine (JA-Ile) specifically promotes COI1-TIFY7/JAZ9 interaction.<ref>PMID:19151223</ref> 
[https://www.uniprot.org/uniprot/MYC3_ARATH MYC3_ARATH] Transcription factor involved in tryptophan, jasmonic acid (JA) and other stress-responsive gene regulation. With MYC2 and MYC4, controls additively subsets of JA-dependent responses. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the G-box (5'-CACGTG-3') of promoters. Activates multiple TIFY/JAZ promoters.<ref>PMID:12136026</ref> <ref>PMID:21242320</ref> <ref>PMID:21321051</ref> <ref>PMID:21335373</ref> <ref>PMID:23943862</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Brunzelle, J S]]
[[Category: Arabidopsis thaliana]]
[[Category: He, S Y]]
[[Category: Large Structures]]
[[Category: Ke, J]]
[[Category: Brunzelle JS]]
[[Category: Melcher, K]]
[[Category: He SY]]
[[Category: Xu, H E]]
[[Category: Ke J]]
[[Category: Zhang, F]]
[[Category: Melcher K]]
[[Category: Helix-sheet-helix sandwich fold]]
[[Category: Xu HE]]
[[Category: Jasmonate signaling]]
[[Category: Zhang F]]
[[Category: Myc transcription factor]]
[[Category: Myc-jaz complex]]
[[Category: Transcription regulator]]

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