1z2k: Difference between revisions

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==NMR structure of the D1 domain of the Natural Killer Cell Receptor, 2B4==
==NMR structure of the D1 domain of the Natural Killer Cell Receptor, 2B4==
<StructureSection load='1z2k' size='340' side='right' caption='[[1z2k]], [[NMR_Ensembles_of_Models | 14 NMR models]]' scene=''>
<StructureSection load='1z2k' size='340' side='right'caption='[[1z2k]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1z2k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z2K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z2K FirstGlance]. <br>
<table><tr><td colspan='2'>[[1z2k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z2K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z2K FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cd244, 2b4, Nmrk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 14 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z2k OCA], [http://pdbe.org/1z2k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1z2k RCSB], [http://www.ebi.ac.uk/pdbsum/1z2k PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z2k OCA], [https://pdbe.org/1z2k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z2k RCSB], [https://www.ebi.ac.uk/pdbsum/1z2k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z2k ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CD244_MOUSE CD244_MOUSE]] Modulate other receptor-ligand interactions to enhance leukocyte activation (By similarity).  
[https://www.uniprot.org/uniprot/CD244_MOUSE CD244_MOUSE] Modulate other receptor-ligand interactions to enhance leukocyte activation (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z2/1z2k_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z2/1z2k_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z2k ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Large Structures]]
[[Category: Ames, J B]]
[[Category: Mus musculus]]
[[Category: Lusin, J D]]
[[Category: Ames JB]]
[[Category: Mariuzza, R]]
[[Category: Lusin JD]]
[[Category: Vyas, V]]
[[Category: Mariuzza R]]
[[Category: Beta sandwich]]
[[Category: Vyas V]]
[[Category: Immune system]]
[[Category: Immunoglobulin motif]]
[[Category: Natural killer cell receptor]]
[[Category: V-domain]]

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