1tu1: Difference between revisions

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-[[Image:1tu1.jpg|left|200px]]
- {{Structure
+==Crystal Structure of Protein of Unknown Function PA94 from Pseudomonas aeruginosa, Putative Regulator==
-|PDB= 1tu1 |SIZE=350|CAPTION= <scene name='initialview01'>1tu1</scene>, resolution 1.95&Aring;
+<StructureSection load='1tu1' size='340' side='right'caption='[[1tu1]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
+<table><tr><td colspan='2'>[[1tu1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TU1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TU1 FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
-|GENE= PA0094 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG5435 COG5435]</span>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tu1 OCA], [https://pdbe.org/1tu1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tu1 RCSB], [https://www.ebi.ac.uk/pdbsum/1tu1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tu1 ProSAT], [https://www.topsan.org/Proteins/MCSG/1tu1 TOPSAN]</span></td></tr>
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tu1 OCA], [http://www.ebi.ac.uk/pdbsum/1tu1 PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1tu1 RCSB]</span>
+</table>
-}}
+== Function ==
+[https://www.uniprot.org/uniprot/EAGT6_PSEAE EAGT6_PSEAE] Plays an essential role in toxin Tse6 delivery to target cells and specifically in the loading of Tse6 onto VgrG1a.<ref>PMID:30177742</ref>
-'''Crystal Structure of Protein of Unknown Function PA94 from Pseudomonas aeruginosa, Putative Regulator'''
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
-==About this Structure==
+  <jmolCheckbox>
-TU1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TU1 OCA].
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tu/1tu1_consurf.spt"</scriptWhenChecked>
-[[Category: Pseudomonas aeruginosa]]
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-[[Category: Single protein]]
+    <text>to colour the structure by Evolutionary Conservation</text>
-[[Category: Cymborowski, M.]]
+  </jmolCheckbox>
-[[Category: Edwards, A.]]
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tu1 ConSurf].
-[[Category: Evdokimova, E.]]
+<div style="clear:both"></div>
-[[Category: Joachimiak, A.]]
+== References ==
-[[Category: MCSG, Midwest Center for Structural Genomics.]]
+<references/>
-[[Category: Minor, W.]]
+__TOC__
-[[Category: Osipiuk, J.]]
+</StructureSection>
-[[Category: Savchenko, A.]]
+[[Category: Large Structures]]
-[[Category: hypothetical protein]]
+[[Category: Pseudomonas aeruginosa PAO1]]
-[[Category: mcsg]]
+[[Category: Cymborowski M]]
-[[Category: midwest center for structural genomic]]
+[[Category: Edwards A]]
-[[Category: pa0094]]
+[[Category: Evdokimova E]]
-[[Category: protein structure initiative]]
+[[Category: Joachimiak A]]
-[[Category: psi]]
+[[Category: Minor W]]
-[[Category: structural genomic]]
+[[Category: Osipiuk J]]
+[[Category: Savchenko A]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:08:00 2008''