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==Solution structure of subunit c of F1Fo-ATP synthase from the thermophilic bacillus PS3==
==Solution structure of subunit c of F1Fo-ATP synthase from the thermophilic bacillus PS3==
<StructureSection load='1wu0' size='340' side='right' caption='[[1wu0]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''>
<StructureSection load='1wu0' size='340' side='right'caption='[[1wu0]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1wu0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacp3 Bacp3]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WU0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WU0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1wu0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp._PS3 Bacillus sp. PS3]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WU0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WU0 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a91|1a91]], [[1c0v|1c0v]], [[1c99|1c99]], [[1c17|1c17]], [[1qo1|1qo1]], [[1aty|1aty]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">atpE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2334 BACP3])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wu0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wu0 OCA], [https://pdbe.org/1wu0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wu0 RCSB], [https://www.ebi.ac.uk/pdbsum/1wu0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wu0 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/H(+)-transporting_two-sector_ATPase H(+)-transporting two-sector ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wu0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wu0 OCA], [http://pdbe.org/1wu0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wu0 RCSB], [http://www.ebi.ac.uk/pdbsum/1wu0 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ATPL_BACP3 ATPL_BACP3]] F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.[HAMAP-Rule:MF_01396]  Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of 10 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.[HAMAP-Rule:MF_01396]  
[https://www.uniprot.org/uniprot/ATPL_BACP3 ATPL_BACP3] F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.[HAMAP-Rule:MF_01396]  Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of 10 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.[HAMAP-Rule:MF_01396]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wu/1wu0_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wu/1wu0_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wu0 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>


==See Also==
==See Also==
*[[ATPase|ATPase]]
*[[ATPase 3D structures|ATPase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacp3]]
[[Category: Bacillus sp. PS3]]
[[Category: Akutsu, H]]
[[Category: Large Structures]]
[[Category: Ikegami, T]]
[[Category: Akutsu H]]
[[Category: Nakano, T]]
[[Category: Ikegami T]]
[[Category: Suzuki, T]]
[[Category: Nakano T]]
[[Category: Yoshida, M]]
[[Category: Suzuki T]]
[[Category: Atp synthase]]
[[Category: Yoshida M]]
[[Category: Atpase]]
[[Category: Hydrogen ion transport]]
[[Category: Hydrolase]]
[[Category: Membrane protein]]

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