1vra: Difference between revisions

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[[Image:1vra.gif|left|200px]]


{{Structure
==Crystal structure of Arginine biosynthesis bifunctional protein argJ (10175521) from Bacillus halodurans at 2.00 A resolution==
|PDB= 1vra |SIZE=350|CAPTION= <scene name='initialview01'>1vra</scene>, resolution 2.00&Aring;
<StructureSection load='1vra' size='340' side='right'caption='[[1vra]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene>
<table><tr><td colspan='2'>[[1vra]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_halodurans Alkalihalobacillus halodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VRA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VRA FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
|GENE= argJ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=86665 Bacillus halodurans])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02152 OAT]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vra OCA], [https://pdbe.org/1vra PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vra RCSB], [https://www.ebi.ac.uk/pdbsum/1vra PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vra ProSAT], [https://www.topsan.org/Proteins/JCSG/1vra TOPSAN]</span></td></tr>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vra OCA], [http://www.ebi.ac.uk/pdbsum/1vra PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1vra RCSB]</span>
</table>
}}
== Function ==
 
[https://www.uniprot.org/uniprot/ARGJ_HALH5 ARGJ_HALH5] Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
'''Crystal structure of Arginine biosynthesis bifunctional protein argJ (10175521) from Bacillus halodurans at 2.00 A resolution'''
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
==About this Structure==
  <jmolCheckbox>
1VRA is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_halodurans Bacillus halodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VRA OCA].  
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vr/1vra_consurf.spt"</scriptWhenChecked>
[[Category: Bacillus halodurans]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Protein complex]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: JCSG, Joint Center for Structural Genomics.]]
  </jmolCheckbox>
[[Category: 10175521]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vra ConSurf].
[[Category: arginine biosynthesis bifunctional protein argj]]
<div style="clear:both"></div>
[[Category: jcsg]]
__TOC__
[[Category: joint center for structural genomic]]
</StructureSection>
[[Category: protein structure initiative]]
[[Category: Alkalihalobacillus halodurans]]
[[Category: psi]]
[[Category: Large Structures]]
[[Category: structural genomic]]
 
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