2rcc: Difference between revisions

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-[[Image:2rcc.jpg|left|200px]]
- {{Structure
+==Crystal structure of putative class I ribonucleotide reductase (NP_241368.1) from Bacillus halodurans at 1.90 A resolution==
-|PDB= 2rcc |SIZE=350|CAPTION= <scene name='initialview01'>2rcc</scene>, resolution 1.900&Aring;
+<StructureSection load='2rcc' size='340' side='right'caption='[[2rcc]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
+<table><tr><td colspan='2'>[[2rcc]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_halodurans_C-125 Alkalihalobacillus halodurans C-125]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RCC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RCC FirstGlance]. <br>
-|ACTIVITY= [http://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1]
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-|GENE= NP_241368.1, nrdB, BH0502 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2 Bacteria])
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-|DOMAIN=[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00657 Ferritin_like], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01049 RNRR2]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rcc OCA], [https://pdbe.org/2rcc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rcc RCSB], [https://www.ebi.ac.uk/pdbsum/2rcc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rcc ProSAT], [https://www.topsan.org/Proteins/JCSG/2rcc TOPSAN]</span></td></tr>
-|RESOURCES=[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rcc OCA], [http://www.ebi.ac.uk/pdbsum/2rcc PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2rcc RCSB]
+</table>
-}}
+== Function ==
+[https://www.uniprot.org/uniprot/RIR2_HALH5 RIR2_HALH5] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rc/2rcc_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rcc ConSurf].
+<div style="clear:both"></div>
-'''Crystal structure of putative class I ribonucleotide reductase (NP_241368.1) from Bacillus halodurans at 1.90 A resolution'''
+==See Also==
+*[[Ribonucleotide reductase 3D structures|Ribonucleotide reductase 3D structures]]
+__TOC__
-==About this Structure==
+</StructureSection>
-RCC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacteria Bacteria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RCC OCA].
+[[Category: Alkalihalobacillus halodurans C-125]]
-[[Category: Bacteria]]
+[[Category: Large Structures]]
-[[Category: Ribonucleoside-diphosphate reductase]]
-[[Category: Single protein]]
-[[Category: JCSG, Joint Center for Structural Genomics.]]
-[[Category: dna replication]]
-[[Category: iron]]
-[[Category: jcsg]]
-[[Category: joint center for structural genomic]]
-[[Category: metal-binding]]
-[[Category: np_241368 1]]
-[[Category: oxidoreductase]]
-[[Category: protein structure initiative]]
-[[Category: psi-2]]
-[[Category: putative class i ribonucleotide reductase]]
-[[Category: ribonucleotide reductase]]
-[[Category: small chain]]
-[[Category: structural genomic]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Mar 25 23:03:35 2008''