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==Central B domain of Rv0899 from Mycobacterium tuberculosis==
==Central B domain of Rv0899 from Mycobacterium tuberculosis==
<StructureSection load='2ksm' size='340' side='right' caption='[[2ksm]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2ksm' size='340' side='right'caption='[[2ksm]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ksm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KSM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KSM FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ksm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KSM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KSM FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MT0922, MTCY31.27, Rv0899 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ksm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ksm OCA], [http://pdbe.org/2ksm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ksm RCSB], [http://www.ebi.ac.uk/pdbsum/2ksm PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ksm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ksm OCA], [https://pdbe.org/2ksm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ksm RCSB], [https://www.ebi.ac.uk/pdbsum/2ksm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ksm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ARFA_MYCTU ARFA_MYCTU] Probably plays a role in ammonia secretion that neutralizes the medium at pH 5.5, although it does not play a direct role in ammonia transport. The OmpA-like domain (196-326) binds M.tuberculosis peptidoglycan. Overexpression in M.bovis or M.smegmatis gives channels with average conductance value of 1,600 +/- 100 pS, but this may not be physiologically relevant.<ref>PMID:12366842</ref> <ref>PMID:17573469</ref> <ref>PMID:21410778</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Porin|Porin]]
*[[Porin 3D structures|Porin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Kolodzik, A]]
[[Category: Large Structures]]
[[Category: Marassi, F M]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Niederweis, M]]
[[Category: Kolodzik A]]
[[Category: Song, H]]
[[Category: Marassi FM]]
[[Category: Teriete, P]]
[[Category: Niederweis M]]
[[Category: Yao, Y]]
[[Category: Song H]]
[[Category: Yu, J]]
[[Category: Teriete P]]
[[Category: Bon domain]]
[[Category: Yao Y]]
[[Category: Membrane protein]]
[[Category: Yu J]]
[[Category: Ompatb]]
[[Category: Transmembrane]]

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