2eor: Difference between revisions

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 ==Solution structure of the C2H2 type zinc finger (region 255-287) of human Zinc finger protein 224==
-<StructureSection load='2eor' size='340' side='right' caption='[[2eor]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+<StructureSection load='2eor' size='340' side='right'caption='[[2eor]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2eor]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EOR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EOR FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2eor]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EOR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EOR FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZNF224 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eor OCA], [http://pdbe.org/2eor PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2eor RCSB], [http://www.ebi.ac.uk/pdbsum/2eor PDBsum], [http://www.topsan.org/Proteins/RSGI/2eor TOPSAN]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eor OCA], [https://pdbe.org/2eor PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eor RCSB], [https://www.ebi.ac.uk/pdbsum/2eor PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eor ProSAT], [https://www.topsan.org/Proteins/RSGI/2eor TOPSAN]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/ZN224_HUMAN ZN224_HUMAN]] May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.<ref>PMID:20587513</ref>
+[https://www.uniprot.org/uniprot/ZN224_HUMAN ZN224_HUMAN] May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.<ref>PMID:20587513</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eo/2eor_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eo/2eor_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eor ConSurf].
 <div style="clear:both"></div>
 == References ==
@@ Line 23: / Line 24: @@
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Abe, H]]
+[[Category: Large Structures]]
-[[Category: Kigawa, T]]
+[[Category: Abe H]]
-[[Category: Kobayashi, N]]
+[[Category: Kigawa T]]
-[[Category: Koshiba, S]]
+[[Category: Kobayashi N]]
-[[Category: Li, H]]
+[[Category: Koshiba S]]
-[[Category: Structural genomic]]
+[[Category: Li H]]
-[[Category: Saito, K]]
+[[Category: Saito K]]
-[[Category: Sato, M]]
+[[Category: Sato M]]
-[[Category: Tochio, N]]
+[[Category: Tochio N]]
-[[Category: Tomizawa, T]]
+[[Category: Tomizawa T]]
-[[Category: Yokoyama, S]]
+[[Category: Yokoyama S]]
-[[Category: National project on protein structural and functional analyse]]
-[[Category: Nppsfa]]
-[[Category: Rsgi]]
-[[Category: Transcription]]
-[[Category: Zf-c2h2]]