NADP-dependent malic enzyme: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

PDBe, Jaime Prilusky, Michal Harel

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-== NADP-dependent malic enzyme ==
+<StructureSection load='3wja' size='340' side='right' caption='The best structure for NADP-dependent malic enzyme shown: [[3wja]]' scene=''>
-<StructureSection load='3wja' size='340' side='right' caption='Caption for this structure' scene=''>
+Best example is PDB entry [[3wja]] and is shown in the viewer.<br>
-Best example is 3wja<br>
+==Catalytic Activity ==
-Molecule NADP-dependent malic enzyme, also known as NADP-ME, NADP-dependent malic enzyme and Malic enzyme 1.
+Oxaloacetate = pyruvate + CO(2).Data source: Uniprot [http://www.uniprot.org/uniprot/P48163 P48163]<br>
-== Function ==
+Or the decarboxylation of malate to pyruvate<ref>PMID:8187880</ref>.
-electron carrier activity<br>
-NADP binding<br>
-ADP binding<br>
-oxaloacetate decarboxylase activity<br>
-NAD binding<br>
-metal ion binding<br>
-oxidoreductase activity<br>
-malate dehydrogenase (decarboxylating) (NADP+) activity<br>
-manganese ion binding<br>
-malate dehydrogenase (decarboxylating) (NAD+) activity<br>
-malic enzyme activity<br>
-== Disease ==
-== Relevance ==
-== Structural highlights ==
 == Biological process ==
 Is involved in the following biological processes:<br>
@@ Line 34: / Line 18: @@
 cellular lipid metabolic process<br>
 == In structures ==
-[[2aw5]]<br>
+NADP-dependent malic enzyme is found in 3 PDB entries<br>
-[[1gq2]]<br>
+*<b>Eukaryota</b> (3 PDB entries): <br>
-[[3wja]]<br>
+**<b>Homo sapiens</b> (2 PDB entries): <br>
-== Structures sorted by organismm ==
+***[[3wja]] <div class="pdb-prints 3wja"></div>
-Homo sapiens: <br>
+***Title: The crystal structure of human cytosolic NADP(+)-dependent malic enzyme in apo form
-[[2aw5]]<br>
+***2.548 A resolution
-[[3wja]]<br>
+***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22NADP-dependent%20malic%20enzyme%22&!chimera:y Search the PDB for NADP-dependent malic enzyme from Homo sapiens]
-Columba livia: <br>
+**<b>Columba livia</b> (1 PDB entries): <br>
-[[1gq2]]<br>
+***[[1gq2]] <div class="pdb-prints 1gq2"></div>
+***Title: MALIC ENZYME FROM PIGEON LIVER
+***2.5 A resolution
+== Alternative names for NADP-dependent malic enzyme ==
+Molecule '''NADP-dependent malic enzyme''', also known as '''NADP-ME''', '''NADP-dependent malic enzyme''' and '''Malic enzyme 1'''.
+== 3D Structures of NADP-dependent malic enzyme ==
+Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
+[[3wja]], [[2aw5]] – hME - human<br />
+[[7x11]], [[7x12]] – hME1 + NADP<br />
+[[8e76]], [[8eyn]] – hME3<br />
+[[8e78]], [[8e8o]], [[8eyo]] – hME3 + NADP<br />
+[[1gq2]] – ME + NADP - pigeon<br />
+[[5ou5]] – ME - maize<br />
-== PDBe Citation Component ==
+== References ==
-<div class="pdbe-citations 1cbs" load="3p8c" data-id="1cbs">3p8c</div>
+<references/>
+[[Category:Topic Page]][[Category:PDBe]]