5dk6: Difference between revisions

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'''Unreleased structure'''


The entry 5dk6 is ON HOLD
==CRYSTAL STRUCTURE OF A 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE (MTA/SAH) NUCLEOSIDASE (MTAN) FROM COLWELLIA PSYCHRERYTHRAEA 34H (CPS_4743, TARGET PSI-029300) IN COMPLEX WITH ADENINE AT 2.27 A RESOLUTION==
 
<StructureSection load='5dk6' size='340' side='right'caption='[[5dk6]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
Authors: Himmel, D.M., Bhosle, R., Toro, R., Ahmed, M., Hillerich, B., Gizzi, A., Garforth, S., Kar, A., Chan, M.K., Lafluer, J., Patel, H., Matikainen, B., Chamala, S., Lim, S., Celikgil, A., Villegas, G., Evans, B., Love, J., Fiser, A., Seidel, R.D., Bonanno, J.B., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5dk6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Colwellia_psychrerythraea_34H Colwellia psychrerythraea 34H]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DK6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DK6 FirstGlance]. <br>
Description: CRYSTAL STRUCTURE OF A 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE (MTA/SAH) NUCLEOSIDASE (MTAN) FROM COLWELLIA PSYCHRERYTHRAEA 34H (CPS_4743, TARGET PSI-029300) AT 2.27 A RESOLUTION
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.27&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
[[Category: Toro, R]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dk6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dk6 OCA], [https://pdbe.org/5dk6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dk6 RCSB], [https://www.ebi.ac.uk/pdbsum/5dk6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dk6 ProSAT]</span></td></tr>
[[Category: Almo, S.C]]
</table>
[[Category: Bhosle, R]]
== Function ==
[[Category: Kar, A]]
[https://www.uniprot.org/uniprot/MTNN_COLP3 MTNN_COLP3] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.[HAMAP-Rule:MF_01684]
[[Category: Matikainen, B]]
__TOC__
[[Category: Ahmed, M]]
</StructureSection>
[[Category: Love, J]]
[[Category: Colwellia psychrerythraea 34H]]
[[Category: Patel, H]]
[[Category: Large Structures]]
[[Category: Garforth, S]]
[[Category: Ahmed M]]
[[Category: Bonanno, J.B]]
[[Category: Almo SC]]
[[Category: Fiser, A]]
[[Category: Bhosle R]]
[[Category: Lim, S]]
[[Category: Bonanno JB]]
[[Category: Seidel, R.D]]
[[Category: Celikgil A]]
[[Category: Gizzi, A]]
[[Category: Chamala S]]
[[Category: Hillerich, B]]
[[Category: Chan MK]]
[[Category: Chamala, S]]
[[Category: Evans B]]
[[Category: Himmel, D.M]]
[[Category: Fiser A]]
[[Category: Chan, M.K]]
[[Category: Garforth S]]
[[Category: Celikgil, A]]
[[Category: Gizzi A]]
[[Category: New York Structural Genomics Research Consortium (Nysgrc)]]
[[Category: Hillerich B]]
[[Category: Lafluer, J]]
[[Category: Himmel DM]]
[[Category: Evans, B]]
[[Category: Kar A]]
[[Category: Villegas, G]]
[[Category: Lafluer J]]
[[Category: Lim S]]
[[Category: Love J]]
[[Category: Matikainen B]]
[[Category: Patel H]]
[[Category: Seidel RD]]
[[Category: Toro R]]
[[Category: Villegas G]]

Latest revision as of 00:45, 29 June 2023

CRYSTAL STRUCTURE OF A 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE (MTA/SAH) NUCLEOSIDASE (MTAN) FROM COLWELLIA PSYCHRERYTHRAEA 34H (CPS_4743, TARGET PSI-029300) IN COMPLEX WITH ADENINE AT 2.27 A RESOLUTIONCRYSTAL STRUCTURE OF A 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE (MTA/SAH) NUCLEOSIDASE (MTAN) FROM COLWELLIA PSYCHRERYTHRAEA 34H (CPS_4743, TARGET PSI-029300) IN COMPLEX WITH ADENINE AT 2.27 A RESOLUTION

Structural highlights

5dk6 is a 1 chain structure with sequence from Colwellia psychrerythraea 34H. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.27Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MTNN_COLP3 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.[HAMAP-Rule:MF_01684]

5dk6, resolution 2.27Å

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OCA