2n51: Difference between revisions
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==NMR structure of the C-terminal region of human eukaryotic elongation factor 1B== | |||
<StructureSection load='2n51' size='340' side='right'caption='[[2n51]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2n51]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N51 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N51 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n51 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n51 OCA], [https://pdbe.org/2n51 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n51 RCSB], [https://www.ebi.ac.uk/pdbsum/2n51 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n51 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/EF1D_HUMAN EF1D_HUMAN] Isoform 1: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome. Isoform 2: Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE). | |||
==See Also== | |||
*[[Elongation factor 3D structures|Elongation factor 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Feng | [[Category: Homo sapiens]] | ||
[[Category: Wu | [[Category: Large Structures]] | ||
[[Category: Feng Y]] | |||
[[Category: Wu H]] | |||
Latest revision as of 09:15, 15 May 2024
NMR structure of the C-terminal region of human eukaryotic elongation factor 1BNMR structure of the C-terminal region of human eukaryotic elongation factor 1B
Structural highlights
FunctionEF1D_HUMAN Isoform 1: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome. Isoform 2: Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE). See Also |
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