NADP-dependent malic enzyme: Difference between revisions

PDBe (talk | contribs)
New page: ==Your Heading Here (maybe something like 'Structure')== <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> This is a default text for you...
 
Michal Harel (talk | contribs)
No edit summary
 
(78 intermediate revisions by 3 users not shown)
Line 1: Line 1:
==Your Heading Here (maybe something like 'Structure')==
<StructureSection load='3wja' size='340' side='right' caption='The best structure for NADP-dependent malic enzyme shown: [[3wja]]' scene=''>
<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''>
Best example is PDB entry [[3wja]] and is shown in the viewer.<br>
This is a default text for your page '''NADP-dependent malic enzyme'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
==Catalytic Activity ==
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
Oxaloacetate = pyruvate + CO(2).Data source: Uniprot [http://www.uniprot.org/uniprot/P48163 P48163]<br>
Or the decarboxylation of malate to pyruvate<ref>PMID:8187880</ref>.


== Function ==
== Biological process ==
Is involved in the following biological processes:<br>
malate metabolic process<br>
oxidation-reduction process<br>
response to carbohydrate<br>
response to hormone<br>
carbohydrate metabolic process<br>
protein tetramerization<br>
regulation of NADP metabolic process<br>
NADP biosynthetic process<br>
small molecule metabolic process<br>
cellular lipid metabolic process<br>
== In structures ==
NADP-dependent malic enzyme is found in 3 PDB entries<br>
*<b>Eukaryota</b> (3 PDB entries): <br>
**<b>Homo sapiens</b> (2 PDB entries): <br>
***[[3wja]] <div class="pdb-prints 3wja"></div>
***Title: The crystal structure of human cytosolic NADP(+)-dependent malic enzyme in apo form
***2.548 A resolution
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22NADP-dependent%20malic%20enzyme%22&!chimera:y Search the PDB for NADP-dependent malic enzyme from Homo sapiens]
**<b>Columba livia</b> (1 PDB entries): <br>
***[[1gq2]] <div class="pdb-prints 1gq2"></div>
***Title: MALIC ENZYME FROM PIGEON LIVER
***2.5 A resolution
== Alternative names for NADP-dependent malic enzyme ==
Molecule '''NADP-dependent malic enzyme''', also known as '''NADP-ME''', '''NADP-dependent malic enzyme''' and '''Malic enzyme 1'''.


== Disease ==
== 3D Structures of NADP-dependent malic enzyme ==


== Relevance ==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}


== Structural highlights ==
[[3wja]], [[2aw5]] – hME - human<br />
[[7x11]], [[7x12]] – hME1 + NADP<br />
[[8e76]], [[8eyn]] – hME3<br />
[[8e78]], [[8e8o]], [[8eyo]] – hME3 + NADP<br />
[[1gq2]] – ME + NADP - pigeon<br />
[[5ou5]] – ME - maize<br />


This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
</StructureSection>
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]][[Category:PDBe]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

PDBe, Jaime Prilusky, Michal Harel