NADP-dependent malic enzyme: Difference between revisions
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<StructureSection load='3wja' size='340' side='right' caption='The best structure for NADP-dependent malic enzyme shown: [[3wja]]' scene=''> | |||
<StructureSection load=' | Best example is PDB entry [[3wja]] and is shown in the viewer.<br> | ||
==Catalytic Activity == | |||
Oxaloacetate = pyruvate + CO(2).Data source: Uniprot [http://www.uniprot.org/uniprot/P48163 P48163]<br> | |||
Or the decarboxylation of malate to pyruvate<ref>PMID:8187880</ref>. | |||
== | == Biological process == | ||
Is involved in the following biological processes:<br> | |||
malate metabolic process<br> | |||
oxidation-reduction process<br> | |||
response to carbohydrate<br> | |||
response to hormone<br> | |||
carbohydrate metabolic process<br> | |||
protein tetramerization<br> | |||
regulation of NADP metabolic process<br> | |||
NADP biosynthetic process<br> | |||
small molecule metabolic process<br> | |||
cellular lipid metabolic process<br> | |||
== In structures == | |||
NADP-dependent malic enzyme is found in 3 PDB entries<br> | |||
*<b>Eukaryota</b> (3 PDB entries): <br> | |||
**<b>Homo sapiens</b> (2 PDB entries): <br> | |||
***[[3wja]] <div class="pdb-prints 3wja"></div> | |||
***Title: The crystal structure of human cytosolic NADP(+)-dependent malic enzyme in apo form | |||
***2.548 A resolution | |||
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22NADP-dependent%20malic%20enzyme%22&!chimera:y Search the PDB for NADP-dependent malic enzyme from Homo sapiens] | |||
**<b>Columba livia</b> (1 PDB entries): <br> | |||
***[[1gq2]] <div class="pdb-prints 1gq2"></div> | |||
***Title: MALIC ENZYME FROM PIGEON LIVER | |||
***2.5 A resolution | |||
== Alternative names for NADP-dependent malic enzyme == | |||
Molecule '''NADP-dependent malic enzyme''', also known as '''NADP-ME''', '''NADP-dependent malic enzyme''' and '''Malic enzyme 1'''. | |||
== | == 3D Structures of NADP-dependent malic enzyme == | ||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | |||
[[3wja]], [[2aw5]] – hME - human<br /> | |||
[[7x11]], [[7x12]] – hME1 + NADP<br /> | |||
[[8e76]], [[8eyn]] – hME3<br /> | |||
[[8e78]], [[8e8o]], [[8eyo]] – hME3 + NADP<br /> | |||
[[1gq2]] – ME + NADP - pigeon<br /> | |||
[[5ou5]] – ME - maize<br /> | |||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]][[Category:PDBe]] |