OspA: Difference between revisions
No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
(One intermediate revision by the same user not shown) | |||
Line 1: | Line 1: | ||
<StructureSection load='1fj1' size='350' side='right' caption='OspA (magenta and cyan) complex with antibody light chain (grey and pink) and heavy chain (green and yellow) ( | <StructureSection load='1fj1' size='350' side='right' caption='OspA (magenta and cyan) complex with antibody light chain (grey and pink) and heavy chain (green and yellow) (PDB code [[1fj1]])' scene=''> | ||
== Outer surface protein A (OspA) of the Lyme disease spirochete bacterium == | == Outer surface protein A (OspA) of the Lyme disease spirochete bacterium == | ||
Line 20: | Line 20: | ||
<scene name='User:Ji_Youn_Park/Loop_1_52/2'>Loop 1</scene> colored red on the 3-D structure, consists of residues 203 to 220. However, a natural variation found on <scene name='User:Ji_Youn_Park/Res208_51/3'>residue 208</scene> colored yellow, of the first loop is a significant limiting factor in the antibody binding. <scene name='User:Ji_Youn_Park/Loop_2_51/3'>Loop 2</scene>, colored purple, consists of residues 224 to 233. And <scene name='User:Ji_Youn_Park/Loop_3_51/4'>Loop 3</scene> colored blue, consists of residues 246 to 257. The remainder of the beta sheets was colored cyan because they did not play any significant role in OspA. This prototype suggests the importance of the three specific loops and their purpose to binding. | <scene name='User:Ji_Youn_Park/Loop_1_52/2'>Loop 1</scene> colored red on the 3-D structure, consists of residues 203 to 220. However, a natural variation found on <scene name='User:Ji_Youn_Park/Res208_51/3'>residue 208</scene> colored yellow, of the first loop is a significant limiting factor in the antibody binding. <scene name='User:Ji_Youn_Park/Loop_2_51/3'>Loop 2</scene>, colored purple, consists of residues 224 to 233. And <scene name='User:Ji_Youn_Park/Loop_3_51/4'>Loop 3</scene> colored blue, consists of residues 246 to 257. The remainder of the beta sheets was colored cyan because they did not play any significant role in OspA. This prototype suggests the importance of the three specific loops and their purpose to binding. | ||
==3D structures== | |||
See [[Outer surface protein]] | |||
== References == | == References == |