3c96: Difference between revisions

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-[[Image:3c96.jpg|left|200px]]
- {{Structure
+==Crystal structure of the flavin-containing monooxygenase phzS from Pseudomonas aeruginosa. Northeast Structural Genomics Consortium target PaR240==
-|PDB= 3c96 |SIZE=350|CAPTION= <scene name='initialview01'>3c96</scene>, resolution 1.90&Aring;
+<StructureSection load='3c96' size='340' side='right'caption='[[3c96]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-|SITE= <scene name='pdbsite=AC1:Fad+Binding+Site+For+Residue+A+501'>AC1</scene>
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=FAD:FLAVIN-ADENINE DINUCLEOTIDE'>FAD</scene>
+<table><tr><td colspan='2'>[[3c96]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C96 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C96 FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-|GENE= phzS, PA4217 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 Pseudomonas aeruginosa PAO1])
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
-}}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c96 OCA], [https://pdbe.org/3c96 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c96 RCSB], [https://www.ebi.ac.uk/pdbsum/3c96 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c96 ProSAT], [https://www.topsan.org/Proteins/NESGC/3c96 TOPSAN]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PHZS_PSEAE PHZS_PSEAE] Involved in the biosynthesis of pyocyanine, a blue-pigmented phenazine derivative, which plays a role in virulence. Catalyzes the oxidative decarboxylation of 5-methylphenazine-1-carboxylate (5-methyl-PCA) to pyocyanine. Can also act on phenazine-1-carboxylate (PCA), converting it into 1-hydroxyphenazine (1-HP). However, PCA is a poor substrate.<ref>PMID:17253782</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c9/3c96_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c96 ConSurf].
+<div style="clear:both"></div>
-'''Crystal structure of the flavin-containing monooxygenase phzS from Pseudomonas aeruginosa. Northeast Structural Genomics Consortium target PaR240'''
+==See Also==
+*[[Monooxygenase 3D structures|Monooxygenase 3D structures]]
+== References ==
-==About this Structure==
+<references/>
-C96 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C96 OCA].
+__TOC__
-[[Category: Pseudomonas aeruginosa pao1]]
+</StructureSection>
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Acton, T B.]]
+[[Category: Pseudomonas aeruginosa PAO1]]
-[[Category: Chen, Y.]]
+[[Category: Acton TB]]
-[[Category: Hunt, J F.]]
+[[Category: Chen Y]]
-[[Category: Mao, L.]]
+[[Category: Hunt JF]]
-[[Category: Montelione, G T.]]
+[[Category: Mao L]]
-[[Category: NESG, Northeast Structural Genomics Consortium.]]
+[[Category: Montelione GT]]
-[[Category: Seetharaman, J.]]
+[[Category: Seetharaman J]]
-[[Category: Tong, L.]]
+[[Category: Tong L]]
-[[Category: Vorobiev, S M.]]
+[[Category: Vorobiev SM]]
-[[Category: Wang, D.]]
+[[Category: Wang D]]
-[[Category: Xiao, R.]]
+[[Category: Xiao R]]
-[[Category: FAD]]
-[[Category: fad]]
-[[Category: monooxygenase]]
-[[Category: nesg]]
-[[Category: northeast structural genomics consortium]]
-[[Category: oxidoreductase]]
-[[Category: par240]]
-[[Category: pf01266]]
-[[Category: protein structure initiative]]
-[[Category: psi-2]]
-[[Category: structural genomic]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:03:02 2008''