5bo2: Difference between revisions

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-'''Unreleased structure'''
-The entry 5bo2 is ON HOLD  until Paper Publication
+==Bianthranilate-like inhibitor with 4-atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)==
+<StructureSection load='5bo2' size='340' side='right'caption='[[5bo2]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5bo2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Ra Mycobacterium tuberculosis H37Ra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BO2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BO2 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7P1:2-[(2-CARBOXYPHENYL)AMINO]-5-(3-PHOSPHONOPROPOXY)BENZOIC+ACID'>7P1</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bo2 OCA], [https://pdbe.org/5bo2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bo2 RCSB], [https://www.ebi.ac.uk/pdbsum/5bo2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bo2 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TRPD_MYCTA TRPD_MYCTA] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
-Authors: Evans, G.L., Baker, E.N., Lott, J.S., TB Structural Genomics Consortium (TBSGC)
+==See Also==
+*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
-Description:
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Lott, J.S]]
+[[Category: Large Structures]]
-[[Category: Evans, G.L]]
+[[Category: Mycobacterium tuberculosis H37Ra]]
-[[Category: Baker, E.N]]
+[[Category: Baker EN]]
-[[Category: Tb Structural Genomics Consortium (Tbsgc)]]
+[[Category: Evans GL]]
+[[Category: Lott JS]]