4z6i: Difference between revisions
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==Crystal structure of BRD9 bromodomain in complex with a substituted valerolactam quinolone ligand== | ==Crystal structure of BRD9 bromodomain in complex with a substituted valerolactam quinolone ligand== | ||
<StructureSection load='4z6i' size='340' side='right' caption='[[4z6i]], [[Resolution|resolution]] 1.95Å' scene=''> | <StructureSection load='4z6i' size='340' side='right'caption='[[4z6i]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4z6i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z6I OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[4z6i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z6I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Z6I FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4L3:TERT-BUTYL+[(2R,3S)-1-(1,4-DIMETHYL-2-OXO-1,2-DIHYDROQUINOLIN-7-YL)-6-OXO-2-PHENYLPIPERIDIN-3-YL]CARBAMATE'>4L3</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4L3:TERT-BUTYL+[(2R,3S)-1-(1,4-DIMETHYL-2-OXO-1,2-DIHYDROQUINOLIN-7-YL)-6-OXO-2-PHENYLPIPERIDIN-3-YL]CARBAMATE'>4L3</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4z6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z6i OCA], [https://pdbe.org/4z6i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4z6i RCSB], [https://www.ebi.ac.uk/pdbsum/4z6i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4z6i ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/BRD9_HUMAN BRD9_HUMAN] May play a role in chromatin remodeling and regulation of transcription. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 16: | Line 18: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 4z6i" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Arrowsmith CH]] | ||
[[Category: | [[Category: Bountra C]] | ||
[[Category: | [[Category: Brennan PE]] | ||
[[Category: Dixon | [[Category: Clark PGK]] | ||
[[Category: Edwards | [[Category: Dixon DJ]] | ||
[[Category: Fedorov | [[Category: Edwards AM]] | ||
[[Category: Knapp | [[Category: Fedorov O]] | ||
[[Category: Krojer | [[Category: Knapp S]] | ||
[[Category: Newman | [[Category: Krojer T]] | ||
[[Category: Nunez-Alonso | [[Category: Newman JA]] | ||
[[Category: Picaud | [[Category: Nunez-Alonso G]] | ||
[[Category: Picaud S]] | |||
[[Category: Tallant | [[Category: Tallant C]] | ||
[[Category: Vieira | [[Category: Vieira LCC]] | ||
[[Category: | [[Category: Von Delft F]] | ||