4z2a: Difference between revisions
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==Crystal structure of unglycosylated apo human furin @1.89A== | |||
<StructureSection load='4z2a' size='340' side='right'caption='[[4z2a]], [[Resolution|resolution]] 1.89Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4z2a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z2A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Z2A FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4z2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z2a OCA], [https://pdbe.org/4z2a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4z2a RCSB], [https://www.ebi.ac.uk/pdbsum/4z2a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4z2a ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/FURIN_HUMAN FURIN_HUMAN] Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif.<ref>PMID:7690548</ref> | |||
==See Also== | |||
*[[Furin|Furin]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Reid | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | |||
[[Category: Gampe RT]] | |||
[[Category: Pearce K]] | |||
[[Category: Reid R]] |