3j9c: Difference between revisions
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==CryoEM single particle reconstruction of anthrax toxin protective antigen pore at 2.9 Angstrom resolution== | ==CryoEM single particle reconstruction of anthrax toxin protective antigen pore at 2.9 Angstrom resolution== | ||
< | <SX load='3j9c' size='340' side='right' viewer='molstar' caption='[[3j9c]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3j9c]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J9C OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[3j9c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J9C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J9C FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j9c OCA], [https://pdbe.org/3j9c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j9c RCSB], [https://www.ebi.ac.uk/pdbsum/3j9c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j9c ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/PAG_BACAN PAG_BACAN] One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax. | ||
__TOC__ | __TOC__ | ||
</ | </SX> | ||
[[Category: | [[Category: Bacillus anthracis]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Collier RJ]] | ||
[[Category: | [[Category: Jiang J]] | ||
[[Category: | [[Category: Pentelute BL]] | ||
[[Category: | [[Category: Zhou ZH]] | ||