3j9c: Difference between revisions

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==CryoEM single particle reconstruction of anthrax toxin protective antigen pore at 2.9 Angstrom resolution==
==CryoEM single particle reconstruction of anthrax toxin protective antigen pore at 2.9 Angstrom resolution==
<StructureSection load='3j9c' size='340' side='right' caption='[[3j9c]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<SX load='3j9c' size='340' side='right' viewer='molstar' caption='[[3j9c]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3j9c]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J9C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3J9C FirstGlance]. <br>
<table><tr><td colspan='2'>[[3j9c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J9C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J9C FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j9c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j9c RCSB], [http://www.ebi.ac.uk/pdbsum/3j9c PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j9c OCA], [https://pdbe.org/3j9c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j9c RCSB], [https://www.ebi.ac.uk/pdbsum/3j9c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j9c ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PAG_BACAN PAG_BACAN]] One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax.  
[https://www.uniprot.org/uniprot/PAG_BACAN PAG_BACAN] One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax.
__TOC__
__TOC__
</StructureSection>
</SX>
[[Category: Collier, R J]]
[[Category: Bacillus anthracis]]
[[Category: Jiang, J]]
[[Category: Large Structures]]
[[Category: Pentelute, B L]]
[[Category: Collier RJ]]
[[Category: Zhou, Z H]]
[[Category: Jiang J]]
[[Category: Anthrax toxin]]
[[Category: Pentelute BL]]
[[Category: Bacterial toxin]]
[[Category: Zhou ZH]]
[[Category: Protective antigen]]
[[Category: Protein translocation channel]]
[[Category: Toxin]]
[[Category: Transport protein]]

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