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==CRYSTAL STRUCTURE OF A TRAP PERIPLASMIC SOLUTE BINDING PROTEIN FROM DESULFOVIBRIO ALASKENSIS G20 (Dde_0634, TARGET EFI-510120) WITH BOUND 3-INDOLE ACETIC ACID==
==CRYSTAL STRUCTURE OF A TRAP PERIPLASMIC SOLUTE BINDING PROTEIN FROM DESULFOVIBRIO ALASKENSIS G20 (Dde_0634, TARGET EFI-510120) WITH BOUND 3-INDOLE ACETIC ACID==
<StructureSection load='4pgp' size='340' side='right' caption='[[4pgp]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
<StructureSection load='4pgp' size='340' side='right'caption='[[4pgp]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4pgp]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PGP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PGP FirstGlance]. <br>
<table><tr><td colspan='2'>[[4pgp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Oleidesulfovibrio_alaskensis_G20 Oleidesulfovibrio alaskensis G20]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PGP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PGP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IAC:1H-INDOL-3-YLACETIC+ACID'>IAC</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pgp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pgp RCSB], [http://www.ebi.ac.uk/pdbsum/4pgp PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IAC:1H-INDOL-3-YLACETIC+ACID'>IAC</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pgp OCA], [https://pdbe.org/4pgp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pgp RCSB], [https://www.ebi.ac.uk/pdbsum/4pgp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pgp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DCTP2_OLEA2 DCTP2_OLEA2] Solute-binding protein that binds indole-3-pyruvate and indole-3-acetate (in vitro). Can also bind D-tryptophan (in vitro), but that is probably not a physiological ligand (PubMed:25540822). Probably part of a tripartite ATP-independent periplasmic (TRAP) transport system that mediates solute transport into the cytoplasm.<ref>PMID:25540822</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4pgp" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Almo, S C]]
[[Category: Large Structures]]
[[Category: Attonito, J D]]
[[Category: Oleidesulfovibrio alaskensis G20]]
[[Category: Chowdhury, S]]
[[Category: Al Obaidi NF]]
[[Category: EFI, Enzyme Function Initiative]]
[[Category: Almo SC]]
[[Category: Evans, B]]
[[Category: Attonito JD]]
[[Category: Gerlt, J A]]
[[Category: Chowdhury S]]
[[Category: Glenn, A Scott]]
[[Category: Evans B]]
[[Category: Hillerich, B]]
[[Category: Gerlt JA]]
[[Category: Love, J]]
[[Category: Hillerich B]]
[[Category: Morisco, L L]]
[[Category: Love J]]
[[Category: Obaidi, N F.Al]]
[[Category: Morisco LL]]
[[Category: Seidel, R D]]
[[Category: Scott Glenn A]]
[[Category: Stead, M]]
[[Category: Seidel RD]]
[[Category: Vetting, M W]]
[[Category: Stead M]]
[[Category: Wasserman, S R]]
[[Category: Vetting MW]]
[[Category: Whalen, K L]]
[[Category: Wasserman SR]]
[[Category: Efi]]
[[Category: Whalen KL]]
[[Category: Enzyme function initiative]]
[[Category: Structural genomic]]
[[Category: Trap periplasmic solute binding family]]

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