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==Structure of Aspergillus oryzae AA11 Lytic Polysaccharide Monooxygenase with Zn==
==Structure of Aspergillus oryzae AA11 Lytic Polysaccharide Monooxygenase with Zn==
<StructureSection load='4mah' size='340' side='right' caption='[[4mah]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
<StructureSection load='4mah' size='340' side='right'caption='[[4mah]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4mah]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspoz Aspoz]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MAH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MAH FirstGlance]. <br>
<table><tr><td colspan='2'>[[4mah]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_oryzae Aspergillus oryzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MAH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MAH FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mai|4mai]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AO090102000501 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5062 ASPOZ])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mah FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mah OCA], [https://pdbe.org/4mah PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mah RCSB], [https://www.ebi.ac.uk/pdbsum/4mah PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mah ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mah FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mah OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mah RCSB], [http://www.ebi.ac.uk/pdbsum/4mah PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LP11_ASPOR LP11_ASPOR] Lytic polysaccharide monooxygenase (LPMO) that depolymerizes chitin via the oxidation of scissile beta-(1-4)-glycosidic bonds, yielding C1 or C4 oxidation products (PubMed:24362702). Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate (PubMed:24362702). Active on chitin but has no activity on other substrates, including diverse mannans, cellulose and starch (data not shown) (PubMed:24362702). Primary chain cleavage yields predominantly aldonic acid oligosaccharides with even-numbered degrees of polymerization (PubMed:24362702).<ref>PMID:24362702</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
<div class="pdbe-citations 4mah" style="background-color:#fffaf0;"></div>
==See Also==
*[[Monooxygenase 3D structures|Monooxygenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aspoz]]
[[Category: Aspergillus oryzae]]
[[Category: Davies, G J]]
[[Category: Large Structures]]
[[Category: Hemsworth, G R]]
[[Category: Davies GJ]]
[[Category: Henrissat, B]]
[[Category: Hemsworth GR]]
[[Category: Walton, P H]]
[[Category: Henrissat B]]
[[Category: Aa11]]
[[Category: Walton PH]]
[[Category: Chitin degradation]]
[[Category: Chitin oxidation]]
[[Category: Gh61]]
[[Category: Oxidoreductase]]

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