2ph5: Difference between revisions

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-[[Image:2ph5.gif|left|200px]]
- {{Structure
+==Crystal structure of the homospermidine synthase hss from Legionella pneumophila in complex with NAD, Northeast Structural Genomics Target LgR54==
-|PDB= 2ph5 |SIZE=350|CAPTION= <scene name='initialview01'>2ph5</scene>, resolution 2.50&Aring;
+<StructureSection load='2ph5' size='340' side='right'caption='[[2ph5]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>
+<table><tr><td colspan='2'>[[2ph5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Legph Legph]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PH5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PH5 FirstGlance]. <br>
-|ACTIVITY= [http://en.wikipedia.org/wiki/Homospermidine_synthase Homospermidine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.44 2.5.1.44]
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-|GENE= hss, lpg2495 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=91891 Legionella pneumophila subsp. pneumophila])
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-}}
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hss, lpg2495 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272624 LEGPH])</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Homospermidine_synthase Homospermidine synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.44 2.5.1.44] </span></td></tr>
-'''Crystal structure of the homospermidine synthase hss from Legionella pneumophila in complex with NAD, Northeast Structural Genomics Target LgR54'''
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ph5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ph5 OCA], [https://pdbe.org/2ph5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ph5 RCSB], [https://www.ebi.ac.uk/pdbsum/2ph5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ph5 ProSAT], [https://www.topsan.org/Proteins/NESGC/2ph5 TOPSAN]</span></td></tr>
+</table>
+== Evolutionary Conservation ==
-==About this Structure==
+[[Image:Consurf_key_small.gif|200px|right]]
-PH5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila Legionella pneumophila subsp. pneumophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PH5 OCA].
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ph/2ph5_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ph5 ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
 [[Category: Homospermidine synthase]]
-[[Category: Legionella pneumophila subsp. pneumophila]]
+[[Category: Large Structures]]
-[[Category: Single protein]]
+[[Category: Legph]]
-[[Category: Acton, T B.]]
+[[Category: Acton, T B]]
-[[Category: Baran, M C.]]
+[[Category: Baran, M C]]
-[[Category: Cunningham, K.]]
+[[Category: Cunningham, K]]
-[[Category: Fang, Y.]]
+[[Category: Fang, Y]]
-[[Category: Forouhar, F.]]
+[[Category: Forouhar, F]]
-[[Category: Hunt, J F.]]
+[[Category: Hunt, J F]]
-[[Category: Hussain, M.]]
+[[Category: Hussain, M]]
-[[Category: Janjua, H.]]
+[[Category: Janjua, H]]
-[[Category: Liu, J.]]
+[[Category: Liu, J]]
-[[Category: Ma, L-C.]]
+[[Category: Ma, L C]]
-[[Category: Montelione, G T.]]
+[[Category: Montelione, G T]]
-[[Category: NESG, Northeast Structural Genomics Consortium.]]
+[[Category: Structural genomic]]
-[[Category: Owens, L.]]
+[[Category: Owens, L]]
-[[Category: Seetharaman, J.]]
+[[Category: Seetharaman, J]]
-[[Category: Tong, L.]]
+[[Category: Tong, L]]
-[[Category: Xiao, R.]]
+[[Category: Xiao, R]]
-[[Category: NAD]]
+[[Category: Alpha-beta protein]]
-[[Category: SO4]]
+[[Category: Nesg]]
-[[Category: alpha-beta protein]]
+[[Category: PSI, Protein structure initiative]]
-[[Category: nesg]]
+[[Category: Transferase]]
-[[Category: northeast structural genomics consortium]]
-[[Category: protein structure initiative]]
-[[Category: psi-2]]
-[[Category: structural genomic]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:12:54 2008''