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==Crystal structure of dengue 2 virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE2 A11==
==Crystal structure of dengue 2 virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE2 A11==
<StructureSection load='4utb' size='340' side='right' caption='[[4utb]], [[Resolution|resolution]] 3.85&Aring;' scene=''>
<StructureSection load='4utb' size='340' side='right'caption='[[4utb]], [[Resolution|resolution]] 3.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4utb]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UTB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UTB FirstGlance]. <br>
<table><tr><td colspan='2'>[[4utb]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_2 Dengue virus 2] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UTB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UTB FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.85&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uta|4uta]], [[4utc|4utc]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4utb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4utb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4utb RCSB], [http://www.ebi.ac.uk/pdbsum/4utb PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4utb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4utb OCA], [https://pdbe.org/4utb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4utb RCSB], [https://www.ebi.ac.uk/pdbsum/4utb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4utb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A0B4SHY9_9FLAV A0A0B4SHY9_9FLAV]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4utb" style="background-color:#fffaf0;"></div>
==See Also==
*[[Antibody 3D structures|Antibody 3D structures]]
*[[3D structures of human antibody|3D structures of human antibody]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Barba-Spaeth, G]]
[[Category: Dengue virus 2]]
[[Category: Duquerroy, S]]
[[Category: Homo sapiens]]
[[Category: Guardado-Calvo, P]]
[[Category: Large Structures]]
[[Category: Rey, F A]]
[[Category: Barba-Spaeth G]]
[[Category: Rouvinski, A]]
[[Category: Duquerroy S]]
[[Category: Vaney, M C]]
[[Category: Guardado-Calvo P]]
[[Category: Broadly neutralizing antibody]]
[[Category: Rey FA]]
[[Category: Class 2 fusion protein]]
[[Category: Rouvinski A]]
[[Category: Dengue virus]]
[[Category: Vaney MC]]
[[Category: Fab fragment]]
[[Category: Immune system]]
[[Category: Immune system-viral protein complex]]
[[Category: Membrane fusion]]
[[Category: Viral protein]]

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