4rzr: Difference between revisions

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-'''Unreleased structure'''
-The entry 4rzr is ON HOLD  until Paper Publication
+==Bypass of a bulky adduct dG1,8 by DPO4==
+<StructureSection load='4rzr' size='340' side='right'caption='[[4rzr]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4rzr]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RZR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RZR FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2JV:N-(8-AMINOPYREN-1-YL)-2-DEOXY-5-O-(TRIHYDROXY-LAMBDA~5~-PHOSPHANYL)GUANOSINE'>2JV</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DCP:2-DEOXYCYTIDINE-5-TRIPHOSPHATE'>DCP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rzr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rzr OCA], [https://pdbe.org/4rzr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rzr RCSB], [https://www.ebi.ac.uk/pdbsum/4rzr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rzr ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DPO4_SACS2 DPO4_SACS2] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. It is involved in translesional synthesis.
-Authors: Vyas, R., Suo, Z.
+==See Also==
+*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
-Description: Bypass of a bulky adduct dG1,8 by DPO4
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Suo, Z]]
+[[Category: Large Structures]]
-[[Category: Vyas, R]]
+[[Category: Saccharolobus solfataricus P2]]
+[[Category: Synthetic construct]]
+[[Category: Suo Z]]
+[[Category: Vyas R]]