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[[Image:2omd.jpg|left|200px]]


{{Structure
==Crystal structure of molybdopterin converting factor subunit 2 (aq_2181) from aquifex aeolicus VF5==
|PDB= 2omd |SIZE=350|CAPTION= <scene name='initialview01'>2omd</scene>, resolution 2.00&Aring;
<StructureSection load='2omd' size='340' side='right'caption='[[2omd]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:Na+Binding+Site+For+Residue+A+701'>AC1</scene>, <scene name='pdbsite=AC2:Na+Binding+Site+For+Residue+B+702'>AC2</scene>, <scene name='pdbsite=AC3:Cl+Binding+Site+For+Residue+A+800'>AC3</scene>, <scene name='pdbsite=AC4:Trs+Binding+Site+For+Residue+A+603'>AC4</scene>, <scene name='pdbsite=AC5:Gol+Binding+Site+For+Residue+B+601'>AC5</scene>, <scene name='pdbsite=AC6:Gol+Binding+Site+For+Residue+B+602'>AC6</scene>, <scene name='pdbsite=AC7:Fmt+Binding+Site+For+Residue+A+604'>AC7</scene> and <scene name='pdbsite=AC8:Fmt+Binding+Site+For+Residue+B+605'>AC8</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
<table><tr><td colspan='2'>[[2omd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OMD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OMD FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2omd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2omd OCA], [https://pdbe.org/2omd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2omd RCSB], [https://www.ebi.ac.uk/pdbsum/2omd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2omd ProSAT], [https://www.topsan.org/Proteins/RSGI/2omd TOPSAN]</span></td></tr>
 
</table>
'''Crystal structure of molybdopterin converting factor subunit 2 (aq_2181) from aquifex aeolicus VF5'''
== Function ==
 
[https://www.uniprot.org/uniprot/MOAE_AQUAE MOAE_AQUAE] Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity).
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2OMD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OMD OCA].
Check<jmol>
[[Category: Aquifex aeolicus]]
  <jmolCheckbox>
[[Category: Single protein]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/om/2omd_consurf.spt"</scriptWhenChecked>
[[Category: Agari, Y.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Ebihara, A.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Jeyakanthan, J.]]
  </jmolCheckbox>
[[Category: Kanaujia, S P.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2omd ConSurf].
[[Category: Kuramitsu, S.]]
<div style="clear:both"></div>
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
__TOC__
[[Category: Ranjani, C Vasuki.]]
</StructureSection>
[[Category: Sekar, K.]]
[[Category: Aquifex aeolicus VF5]]
[[Category: Shinkai, A.]]
[[Category: Large Structures]]
[[Category: Shiro, Y.]]
[[Category: Agari Y]]
[[Category: Yokoyama, S.]]
[[Category: Ebihara A]]
[[Category: CL]]
[[Category: Jeyakanthan J]]
[[Category: FMT]]
[[Category: Kanaujia SP]]
[[Category: GOL]]
[[Category: Kuramitsu S]]
[[Category: NA]]
[[Category: Sekar K]]
[[Category: TRS]]
[[Category: Shinkai A]]
[[Category: coenzyme biosynthesis]]
[[Category: Shiro Y]]
[[Category: lyase]]
[[Category: Vasuki Ranjani C]]
[[Category: moae]]
[[Category: Yokoyama S]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
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