2w9d: Difference between revisions

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==STRUCTURE OF FAB FRAGMENT OF THE ICSM 18 - ANTI-PRP THERAPEUTIC ANTIBODY AT 1.57 A RESOLUTION.==
 
<StructureSection load='2w9d' size='340' side='right' caption='[[2w9d]], [[Resolution|resolution]] 1.57&Aring;' scene=''>
==Structure of Fab fragment of the ICSM 18 - anti-Prp therapeutic antibody at 1.57 A resolution.==
<StructureSection load='2w9d' size='340' side='right'caption='[[2w9d]], [[Resolution|resolution]] 1.57&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2w9d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W9D FirstGlance]. <br>
<table><tr><td colspan='2'>[[2w9d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W9D FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.57&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2w9e|2w9e]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w9d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9d OCA], [https://pdbe.org/2w9d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w9d RCSB], [https://www.ebi.ac.uk/pdbsum/2w9d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w9d ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w9d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w9d RCSB], [http://www.ebi.ac.uk/pdbsum/2w9d PDBsum]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/2w9d_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/2w9d_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w9d ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2w9d" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Antibody|Antibody]]
*[[Antibody 3D structures|Antibody 3D structures]]
*[[Sandbox 20009|Sandbox 20009]]
*[[3D structures of non-human antibody|3D structures of non-human antibody]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Antonyuk, S V]]
[[Category: Antonyuk SV]]
[[Category: Batchelor, M]]
[[Category: Batchelor M]]
[[Category: Clarke, A R]]
[[Category: Clarke AR]]
[[Category: Collinge, J]]
[[Category: Collinge J]]
[[Category: Cooper, S]]
[[Category: Cooper S]]
[[Category: Fraser, C]]
[[Category: Fraser C]]
[[Category: Georgiou, T]]
[[Category: Georgiou T]]
[[Category: Hasnain, S S]]
[[Category: Hasnain SS]]
[[Category: Jackson, G S]]
[[Category: Jackson GS]]
[[Category: Jones, S]]
[[Category: Jones S]]
[[Category: Khalili-Shirazi, A]]
[[Category: Khalili-Shirazi A]]
[[Category: Sangar, D]]
[[Category: Sangar D]]
[[Category: Strange, R W]]
[[Category: Strange RW]]
[[Category: Trevitt, C R]]
[[Category: Trevitt CR]]
[[Category: Fab]]
[[Category: Immune system]]
[[Category: Prion]]
[[Category: Prp]]

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