2j5c: Difference between revisions

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==RATIONAL CONVERSION OF SUBSTRATE AND PRODUCT SPECIFICITY IN A MONOTERPENE SYNTHASE. STRUCTURAL INSIGHTS INTO THE MOLECULAR BASIS OF RAPID EVOLUTION.==
 
<StructureSection load='2j5c' size='340' side='right' caption='[[2j5c]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
==Rational conversion of substrate and product specificity in a monoterpene synthase. Structural insights into the molecular basis of rapid evolution.==
<StructureSection load='2j5c' size='340' side='right'caption='[[2j5c]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2j5c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salvia_fruticosa Salvia fruticosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J5C FirstGlance]. <br>
<table><tr><td colspan='2'>[[2j5c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salvia_fruticosa Salvia fruticosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J5C FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j5c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2j5c RCSB], [http://www.ebi.ac.uk/pdbsum/2j5c PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j5c OCA], [https://pdbe.org/2j5c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j5c RCSB], [https://www.ebi.ac.uk/pdbsum/2j5c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j5c ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CINS1_SALFT CINS1_SALFT]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j5/2j5c_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j5/2j5c_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2j5c ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2j5c" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Salvia fruticosa]]
[[Category: Salvia fruticosa]]
[[Category: Anssour, S]]
[[Category: Anssour S]]
[[Category: Dunwell, J M]]
[[Category: Dunwell JM]]
[[Category: Goodenough, P W]]
[[Category: Goodenough PW]]
[[Category: Ioannidis, D]]
[[Category: Ioannidis D]]
[[Category: Johnson, C B]]
[[Category: Johnson CB]]
[[Category: Kampranis, S C]]
[[Category: Kampranis SC]]
[[Category: Katerelos, N A]]
[[Category: Katerelos NA]]
[[Category: Mahrez, W]]
[[Category: Mahrez W]]
[[Category: Makris, A M]]
[[Category: Makris AM]]
[[Category: Ninga, E]]
[[Category: Ninga E]]
[[Category: Purvis, A]]
[[Category: Purvis A]]
[[Category: 8-cineole]]
[[Category: Lyase]]
[[Category: Monoterpene]]
[[Category: Terpene synthase]]

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