4czm: Difference between revisions
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==C. crescentus MreB, monomeric, AMPPNP== | ==C. crescentus MreB, monomeric, AMPPNP== | ||
<StructureSection load='4czm' size='340' side='right' caption='[[4czm]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='4czm' size='340' side='right'caption='[[4czm]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4czm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CZM OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[4czm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CZM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CZM FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4czm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4czm OCA], [https://pdbe.org/4czm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4czm RCSB], [https://www.ebi.ac.uk/pdbsum/4czm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4czm ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/MREB_CAUVN MREB_CAUVN] Forms membrane-associated dynamic filaments that are essential for cell shape determination (PubMed:14982627, PubMed:17880425, PubMed:24843005). Acts by regulating cell wall synthesis and cell elongation, and thus cell shape (PubMed:14982627, PubMed:17880425). A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature (By similarity). Required for mid-cell peptidoglycan synthesis and cell division. Directs the localization of the cytosolic peptidoglycan precursor-synthesizing enzyme MurG (PubMed:17880425). Also required for proper chromosome segregation (PubMed:15707892). Directs the segregation of origin-proximal but not origin-distal loci (PubMed:15707892).[UniProtKB:P0A9X4]<ref>PMID:14982627</ref> <ref>PMID:15707892</ref> <ref>PMID:17880425</ref> <ref>PMID:24843005</ref> <ref>PMID:14982627</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 4czm" style="background-color:#fffaf0;"></div> | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Caulobacter vibrioides]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Lowe J]] | ||
[[Category: | [[Category: Van den Ent F]] | ||