2gjm: Difference between revisions

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-[[Image:2gjm.gif|left|200px]]
- {{Structure
+==Crystal structure of Buffalo lactoperoxidase at 2.75A resolution==
-|PDB= 2gjm |SIZE=350|CAPTION= <scene name='initialview01'>2gjm</scene>, resolution 2.75&Aring;
+<StructureSection load='2gjm' size='340' side='right'caption='[[2gjm]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene> and <scene name='pdbligand=HEM:PROTOPORPHYRIN IX CONTAINING FE'>HEM</scene>
+<table><tr><td colspan='2'>[[2gjm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bubalus_bubalis Bubalus bubalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GJM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GJM FirstGlance]. <br>
-|ACTIVITY= [http://en.wikipedia.org/wiki/Peroxidase Peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.7 1.11.1.7]
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
-|GENE=
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
-}}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gjm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gjm OCA], [https://pdbe.org/2gjm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gjm RCSB], [https://www.ebi.ac.uk/pdbsum/2gjm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gjm ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PERL_BUBBU PERL_BUBBU] Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN). May protect the udder from infection and promote growth in newborn calves. Inhibits growth of the following bacterial species: E.coli, K.pneumoniae, P.aeruginosa, S.sonnei, S.saphrophyticus, S.epidermidis, and S.dysenteriae.<ref>PMID:12071645</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gj/2gjm_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gjm ConSurf].
+<div style="clear:both"></div>
-'''Crystal structure of Buffalo lactoperoxidase at 2.75A resolution'''
+==See Also==
+*[[Lactoperoxidase|Lactoperoxidase]]
+== References ==
-==About this Structure==
+<references/>
-GJM is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bubalus_bubalis Bubalus bubalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GJM OCA].
+__TOC__
+</StructureSection>
 [[Category: Bubalus bubalis]]
-[[Category: Peroxidase]]
+[[Category: Large Structures]]
-[[Category: Protein complex]]
+[[Category: Ethayathulla AS]]
-[[Category: Ethayathulla, A S.]]
+[[Category: Sharma S]]
-[[Category: Sharma, S.]]
+[[Category: Sheikh IA]]
-[[Category: Sheikh, I A.]]
+[[Category: Singh AK]]
-[[Category: Singh, A K.]]
+[[Category: Singh N]]
-[[Category: Singh, N.]]
+[[Category: Singh TP]]
-[[Category: Singh, T P.]]
-[[Category: CA]]
-[[Category: CO3]]
-[[Category: HEM]]
-[[Category: IOD]]
-[[Category: SCN]]
-[[Category: buffalo]]
-[[Category: crystal structure]]
-[[Category: lactoperoxidase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:05:30 2008''