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==Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with PMP, KYN as substrates and KYA as products== | ==Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with PMP, KYN as substrates and KYA as products== | ||
<StructureSection load='3av7' size='340' side='right' caption='[[3av7]], [[Resolution|resolution]] 1.84Å' scene=''> | <StructureSection load='3av7' size='340' side='right'caption='[[3av7]], [[Resolution|resolution]] 1.84Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3av7]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3av7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AV7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AV7 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KYA:4-HYDROXYQUINOLINE-2-CARBOXYLIC+ACID'>KYA</scene>, <scene name='pdbligand=KYN:(2S)-2-AMINO-4-(2-AMINOPHENYL)-4-OXOBUTANOIC+ACID'>KYN</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.84Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KYA:4-HYDROXYQUINOLINE-2-CARBOXYLIC+ACID'>KYA</scene>, <scene name='pdbligand=KYN:(2S)-2-AMINO-4-(2-AMINOPHENYL)-4-OXOBUTANOIC+ACID'>KYN</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3av7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3av7 OCA], [https://pdbe.org/3av7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3av7 RCSB], [https://www.ebi.ac.uk/pdbsum/3av7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3av7 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/O57946_PYRHO O57946_PYRHO] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Pyrococcus horikoshii]] | [[Category: Pyrococcus horikoshii OT3]] | ||
[[Category: Angkawidjaja | [[Category: Angkawidjaja C]] | ||
[[Category: Kanaya | [[Category: Kanaya S]] | ||
[[Category: Koga | [[Category: Koga Y]] | ||
[[Category: Okada | [[Category: Okada K]] | ||
[[Category: Takano | [[Category: Takano K]] | ||
Latest revision as of 18:57, 4 October 2023
Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with PMP, KYN as substrates and KYA as productsCrystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with PMP, KYN as substrates and KYA as products
Structural highlights
Function |
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