2en9: Difference between revisions

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[[Image:2en9.jpg|left|200px]]


{{Structure
==Solution structure of the C2H2 type zinc finger (region 415-447) of human Zinc finger protein 28 homolog==
|PDB= 2en9 |SIZE=350|CAPTION= <scene name='initialview01'>2en9</scene>
<StructureSection load='2en9' size='340' side='right'caption='[[2en9]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ZN:ZINC ION'>ZN</scene>
<table><tr><td colspan='2'>[[2en9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EN9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EN9 FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= ZFP28 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2en9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2en9 OCA], [https://pdbe.org/2en9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2en9 RCSB], [https://www.ebi.ac.uk/pdbsum/2en9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2en9 ProSAT], [https://www.topsan.org/Proteins/RSGI/2en9 TOPSAN]</span></td></tr>
 
</table>
'''Solution structure of the C2H2 type zinc finger (region 415-447) of human Zinc finger protein 28 homolog'''
== Function ==
 
[https://www.uniprot.org/uniprot/ZFP28_HUMAN ZFP28_HUMAN] May be involved in transcriptional regulation. May have a role in embryonic development.
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2EN9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EN9 OCA].  
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/en/2en9_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2en9 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Abe, H.]]
[[Category: Abe H]]
[[Category: Kigawa, T.]]
[[Category: Kigawa T]]
[[Category: Kobayashi, N.]]
[[Category: Kobayashi N]]
[[Category: Koshiba, S.]]
[[Category: Koshiba S]]
[[Category: Li, H.]]
[[Category: Li H]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Saito K]]
[[Category: Saito, K.]]
[[Category: Sato M]]
[[Category: Sato, M.]]
[[Category: Tochio N]]
[[Category: Tochio, N.]]
[[Category: Tomizawa T]]
[[Category: Tomizawa, T.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: ZN]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nmr]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
[[Category: transcription]]
[[Category: zf-c2h2]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:42:18 2008''

Latest revision as of 21:52, 29 May 2024

Solution structure of the C2H2 type zinc finger (region 415-447) of human Zinc finger protein 28 homologSolution structure of the C2H2 type zinc finger (region 415-447) of human Zinc finger protein 28 homolog

Structural highlights

2en9 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

ZFP28_HUMAN May be involved in transcriptional regulation. May have a role in embryonic development.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Drag the structure with the mouse to rotate

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