2ejc: Difference between revisions

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New page: left|200px {{Structure |PDB= 2ejc |SIZE=350|CAPTION= <scene name='initialview01'>2ejc</scene>, resolution 2.40Å |SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+F...
 
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[[Image:2ejc.jpg|left|200px]]


{{Structure
==Crystal Structure Of Pantoate--Beta-Alanine Ligase (panC) From Thermotoga maritima==
|PDB= 2ejc |SIZE=350|CAPTION= <scene name='initialview01'>2ejc</scene>, resolution 2.40&Aring;
<StructureSection load='2ejc' size='340' side='right'caption='[[2ejc]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+A+501'>AC1</scene>, <scene name='pdbsite=AC2:Zn+Binding+Site+For+Residue+A+502'>AC2</scene>, <scene name='pdbsite=AC3:Zn+Binding+Site+For+Residue+A+503'>AC3</scene>, <scene name='pdbsite=AC4:Zn+Binding+Site+For+Residue+A+504'>AC4</scene>, <scene name='pdbsite=AC5:Zn+Binding+Site+For+Residue+A+505'>AC5</scene>, <scene name='pdbsite=AC6:Zn+Binding+Site+For+Residue+A+506'>AC6</scene>, <scene name='pdbsite=AC7:Zn+Binding+Site+For+Residue+A+507'>AC7</scene>, <scene name='pdbsite=AC8:Zn+Binding+Site+For+Residue+A+508'>AC8</scene>, <scene name='pdbsite=AC9:Zn+Binding+Site+For+Residue+A+509'>AC9</scene>, <scene name='pdbsite=BC1:Zn+Binding+Site+For+Residue+A+510'>BC1</scene>, <scene name='pdbsite=BC2:Zn+Binding+Site+For+Residue+A+511'>BC2</scene>, <scene name='pdbsite=BC3:Zn+Binding+Site+For+Residue+A+512'>BC3</scene>, <scene name='pdbsite=BC4:Zn+Binding+Site+For+Residue+A+513'>BC4</scene>, <scene name='pdbsite=BC5:Zn+Binding+Site+For+Residue+A+515'>BC5</scene>, <scene name='pdbsite=BC6:Zn+Binding+Site+For+Residue+A+516'>BC6</scene>, <scene name='pdbsite=BC7:Zn+Binding+Site+For+Residue+A+517'>BC7</scene>, <scene name='pdbsite=BC8:Zn+Binding+Site+For+Residue+A+518'>BC8</scene>, <scene name='pdbsite=BC9:Zn+Binding+Site+For+Residue+A+519'>BC9</scene>, <scene name='pdbsite=CC1:Zn+Binding+Site+For+Residue+A+521'>CC1</scene>, <scene name='pdbsite=CC2:Zn+Binding+Site+For+Residue+A+522'>CC2</scene> and <scene name='pdbsite=CC3:Act+Binding+Site+For+Residue+A+1101'>CC3</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=ACT:ACETATE ION'>ACT</scene>
<table><tr><td colspan='2'>[[2ejc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EJC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EJC FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Pantoate--beta-alanine_ligase Pantoate--beta-alanine ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.1 6.3.2.1]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
|GENE= panC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 Thermotoga maritima])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ejc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ejc OCA], [https://pdbe.org/2ejc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ejc RCSB], [https://www.ebi.ac.uk/pdbsum/2ejc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ejc ProSAT], [https://www.topsan.org/Proteins/RSGI/2ejc TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PANC_THEMA PANC_THEMA] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ej/2ejc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ejc ConSurf].
<div style="clear:both"></div>


'''Crystal Structure Of Pantoate--Beta-Alanine Ligase (panC) From Thermotoga maritima'''
==See Also==
 
*[[Pantothenate synthetase|Pantothenate synthetase]]
 
__TOC__
==About this Structure==
</StructureSection>
2EJC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EJC OCA].
[[Category: Large Structures]]
[[Category: Pantoate--beta-alanine ligase]]
[[Category: Single protein]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
[[Category: Bagautdinov, B.]]
[[Category: Bagautdinov B]]
[[Category: Kunishima, N.]]
[[Category: Kunishima N]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: ACT]]
[[Category: ZN]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: pantoate-beta-alanine ligase]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
[[Category: x-ray diffraction]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:41:02 2008''

Latest revision as of 11:41, 25 October 2023

Crystal Structure Of Pantoate--Beta-Alanine Ligase (panC) From Thermotoga maritimaCrystal Structure Of Pantoate--Beta-Alanine Ligase (panC) From Thermotoga maritima

Structural highlights

2ejc is a 1 chain structure with sequence from Thermotoga maritima. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.4Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

PANC_THEMA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2ejc, resolution 2.40Å

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