2ee1: Difference between revisions

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-[[Image:2ee1.jpg|left|200px]]
- {{Structure
+==Solution structures of the Chromo domain of human chromodomain helicase-DNA-binding protein 4==
-|PDB= 2ee1 |SIZE=350|CAPTION= <scene name='initialview01'>2ee1</scene>
+<StructureSection load='2ee1' size='340' side='right'caption='[[2ee1]]' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND=
+<table><tr><td colspan='2'>[[2ee1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EE1 FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-|GENE= CHD4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ee1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ee1 OCA], [https://pdbe.org/2ee1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ee1 RCSB], [https://www.ebi.ac.uk/pdbsum/2ee1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ee1 ProSAT], [https://www.topsan.org/Proteins/RSGI/2ee1 TOPSAN]</span></td></tr>
-}}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CHD4_HUMAN CHD4_HUMAN] Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones.<ref>PMID:9804427</ref> <ref>PMID:17626165</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ee/2ee1_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ee1 ConSurf].
+<div style="clear:both"></div>
-'''Solution structures of the Chromo domain of human chromodomain helicase-DNA-binding protein 4'''
+==See Also==
+*[[Chromodomain-helicase-DNA-binding protein 3D structures|Chromodomain-helicase-DNA-binding protein 3D structures]]
+*[[Helicase 3D structures|Helicase 3D structures]]
-==About this Structure==
+== References ==
-EE1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EE1 OCA].
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Harada, T.]]
+[[Category: Harada T]]
-[[Category: Kigawa, T.]]
+[[Category: Kigawa T]]
-[[Category: Koshiba, S.]]
+[[Category: Koshiba S]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+[[Category: Sato M]]
-[[Category: Sato, M.]]
+[[Category: Tochio N]]
-[[Category: Tochio, N.]]
+[[Category: Watanabe S]]
-[[Category: Watanabe, S.]]
+[[Category: Yokoyama S]]
-[[Category: Yokoyama, S.]]
-[[Category: atp- dependent helicase chd4]]
-[[Category: chd-4]]
-[[Category: ec 3 6.1.-]]
-[[Category: mi-2 autoantigen 218 kda protein]]
-[[Category: mi2-beta]]
-[[Category: national project on protein structural and functional analyse]]
-[[Category: nppsfa]]
-[[Category: riken structural genomics/proteomics initiative]]
-[[Category: rsgi]]
-[[Category: signaling protein]]
-[[Category: structural genomic]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:38:52 2008''