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==Crystal structure of tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum== | ==Crystal structure of tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum== | ||
<StructureSection load='3knu' size='340' side='right' caption='[[3knu]], [[Resolution|resolution]] 2.25Å' scene=''> | <StructureSection load='3knu' size='340' side='right'caption='[[3knu]], [[Resolution|resolution]] 2.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3knu]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3knu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Anaplasma_phagocytophilum_str._HZ Anaplasma phagocytophilum str. HZ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KNU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KNU FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3knu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3knu OCA], [https://pdbe.org/3knu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3knu RCSB], [https://www.ebi.ac.uk/pdbsum/3knu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3knu ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/TRMD_ANAPZ TRMD_ANAPZ] Specifically methylates guanosine-37 in various tRNAs (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kn/3knu_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kn/3knu_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3knu ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[TRNA methyltransferase|TRNA methyltransferase]] | *[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Anaplasma phagocytophilum]] | [[Category: Anaplasma phagocytophilum str. HZ]] | ||
[[Category: | [[Category: Large Structures]] | ||
Latest revision as of 11:19, 6 September 2023
Crystal structure of tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilumCrystal structure of tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum
Structural highlights
FunctionTRMD_ANAPZ Specifically methylates guanosine-37 in various tRNAs (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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