3hfh: Difference between revisions
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==Crystal structure of tandem FF domains== | ==Crystal structure of tandem FF domains== | ||
<StructureSection load='3hfh' size='340' side='right' caption='[[3hfh]], [[Resolution|resolution]] 2.70Å' scene=''> | <StructureSection load='3hfh' size='340' side='right'caption='[[3hfh]], [[Resolution|resolution]] 2.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3hfh]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3hfh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HFH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HFH FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.703Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hfh OCA], [https://pdbe.org/3hfh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hfh RCSB], [https://www.ebi.ac.uk/pdbsum/3hfh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hfh ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/TCRG1_HUMAN TCRG1_HUMAN] Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.<ref>PMID:9315662</ref> <ref>PMID:11604498</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 3hfh" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
*[[Elongation factor|Elongation factor]] | *[[Elongation factor 3D structures|Elongation factor 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Bedford | [[Category: Large Structures]] | ||
[[Category: Chen | [[Category: Bedford MT]] | ||
[[Category: Jacobson | [[Category: Chen X]] | ||
[[Category: Lu | [[Category: Jacobson RH]] | ||
[[Category: McMurray | [[Category: Lu M]] | ||
[[Category: Ren | [[Category: McMurray JS]] | ||
[[Category: Subir | [[Category: Ren Z]] | ||
[[Category: Yang | [[Category: Subir S]] | ||
[[Category: Yang J]] | |||