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==2.9A crystal structure of methyl-isocitrate lyase from Burkholderia pseudomallei==
==2.9A crystal structure of methyl-isocitrate lyase from Burkholderia pseudomallei==
<StructureSection load='3eoo' size='340' side='right' caption='[[3eoo]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='3eoo' size='340' side='right'caption='[[3eoo]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3eoo]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_pseudomallei_1655 Burkholderia pseudomallei 1655]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EOO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EOO FirstGlance]. <br>
<table><tr><td colspan='2'>[[3eoo]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_pseudomallei_1655 Burkholderia pseudomallei 1655]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EOO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EOO FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3eol|3eol]], [[3eom|3eom]], [[3eon|3eon]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BURPS1655_C0444, BURPS1710B_2458, BURPS1710b_3237, MSRB, prpB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=331109 Burkholderia pseudomallei 1655])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3eoo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eoo OCA], [https://pdbe.org/3eoo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3eoo RCSB], [https://www.ebi.ac.uk/pdbsum/3eoo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3eoo ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methylisocitrate_lyase Methylisocitrate lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.3.30 4.1.3.30] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3eoo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eoo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3eoo RCSB], [http://www.ebi.ac.uk/pdbsum/3eoo PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/B2H5R7_BURPS B2H5R7_BURPS]] Catalyzes the formation of pyruvate and succinate from 2-methylisocitrate.[RuleBase:RU361121]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eo/3eoo_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eo/3eoo_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3eoo ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Burkholderia pseudomallei 1655]]
[[Category: Burkholderia pseudomallei 1655]]
[[Category: Methylisocitrate lyase]]
[[Category: Large Structures]]
[[Category: Structural genomic]]
[[Category: Burkholderia]]
[[Category: Lyase]]
[[Category: Methyl-isocitrate]]
[[Category: Pseudomallei]]
[[Category: Ssgcid]]

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