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[[Image:2dcg.jpg|left|200px]]


{{Structure
==MOLECULAR STRUCTURE OF A LEFT-HANDED DOUBLE HELICAL DNA FRAGMENT AT ATOMIC RESOLUTION==
|PDB= 2dcg |SIZE=350|CAPTION= <scene name='initialview01'>2dcg</scene>, resolution 0.900&Aring;
<StructureSection load='2dcg' size='340' side='right'caption='[[2dcg]], [[Resolution|resolution]] 0.90&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=SPM:SPERMINE'>SPM</scene>
<table><tr><td colspan='2'>[[2dcg]] is a 2 chain structure. The November 2001 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''DNA''  by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2001_11 10.2210/rcsb_pdb/mom_2001_11]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DCG FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.9&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dcg OCA], [https://pdbe.org/2dcg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dcg RCSB], [https://www.ebi.ac.uk/pdbsum/2dcg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dcg ProSAT]</span></td></tr>
 
</table>
'''MOLECULAR STRUCTURE OF A LEFT-HANDED DOUBLE HELICAL DNA FRAGMENT AT ATOMIC RESOLUTION'''
__TOC__
 
</StructureSection>
 
==Overview==
The DNA fragment d(CpGpCpGpCpG) crystallises as a left-handed double helical molecule with Watson-Crick base pairs and an antiparallel organisation of the sugar phosphate chains. The helix has two nucleotides in the asymmetric unit and contains twelve base pairs per turn. It differs significantly from right-handed B-DNA.
 
==About this Structure==
2DCG is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. The following page contains interesting information on the relation of 2DCG with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb23_1.html DNA]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCG OCA].
 
==Reference==
Molecular structure of a left-handed double helical DNA fragment at atomic resolution., Wang AH, Quigley GJ, Kolpak FJ, Crawford JL, van Boom JH, van der Marel G, Rich A, Nature. 1979 Dec 13;282(5740):680-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/514347 514347]
[[Category: DNA]]
[[Category: DNA]]
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: Boom, J H.Van.]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Crawford, J L.]]
[[Category: Crawford JL]]
[[Category: Kolpak, F J.]]
[[Category: Kolpak FJ]]
[[Category: Marel, G A.Van Der.]]
[[Category: Quigley GJ]]
[[Category: Quigley, G J.]]
[[Category: Rich A]]
[[Category: Rich, A.]]
[[Category: Van Boom JH]]
[[Category: Wang, A H.J.]]
[[Category: Van Der Marel GA]]
[[Category: MG]]
[[Category: Wang AH-J]]
[[Category: SPM]]
[[Category: double helix]]
[[Category: z-dna]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:25:38 2008''

Latest revision as of 12:18, 14 February 2024

MOLECULAR STRUCTURE OF A LEFT-HANDED DOUBLE HELICAL DNA FRAGMENT AT ATOMIC RESOLUTIONMOLECULAR STRUCTURE OF A LEFT-HANDED DOUBLE HELICAL DNA FRAGMENT AT ATOMIC RESOLUTION

Structural highlights

2dcg is a 2 chain structure. The November 2001 RCSB PDB Molecule of the Month feature on DNA by David S. Goodsell is 10.2210/rcsb_pdb/mom_2001_11. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 0.9Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

2dcg, resolution 0.90Å

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