1j55: Difference between revisions
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==The Crystal Structure of Ca+-bound Human S100P Determined at 2.0A Resolution by X-ray== | ==The Crystal Structure of Ca+-bound Human S100P Determined at 2.0A Resolution by X-ray== | ||
<StructureSection load='1j55' size='340' side='right' caption='[[1j55]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='1j55' size='340' side='right'caption='[[1j55]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1j55]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1j55]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J55 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J55 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j55 OCA], [https://pdbe.org/1j55 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j55 RCSB], [https://www.ebi.ac.uk/pdbsum/1j55 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j55 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/S100P_HUMAN S100P_HUMAN] May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).<ref>PMID:14617629</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j5/1j55_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j5/1j55_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j55 ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 1j55" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
*[[S100 | *[[S100 proteins 3D structures|S100 proteins 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Barraclough | [[Category: Large Structures]] | ||
[[Category: Ding | [[Category: Barraclough R]] | ||
[[Category: Fernig | [[Category: Ding Y]] | ||
[[Category: Rao | [[Category: Fernig DG]] | ||
[[Category: Rudland | [[Category: Rao Z]] | ||
[[Category: Wang | [[Category: Rudland PS]] | ||
[[Category: Wang | [[Category: Wang G]] | ||
[[Category: Zhang | [[Category: Wang Z]] | ||
[[Category: Zhang H]] | |||