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==Solution Structure of Methanobacterium Thermoautotrophicum Protein 1598. Ontario Centre for Structural Proteomics target MTH1598_1_140; Northeast Structural Genomics Target TT6==
==Solution Structure of Methanobacterium Thermoautotrophicum Protein 1598. Ontario Centre for Structural Proteomics target MTH1598_1_140; Northeast Structural Genomics Target TT6==
<StructureSection load='1jw3' size='340' side='right' caption='[[1jw3]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='1jw3' size='340' side='right'caption='[[1jw3]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1jw3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JW3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JW3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1jw3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JW3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JW3 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jw3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jw3 RCSB], [http://www.ebi.ac.uk/pdbsum/1jw3 PDBsum], [http://www.topsan.org/Proteins/NESGC/1jw3 TOPSAN]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jw3 OCA], [https://pdbe.org/1jw3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jw3 RCSB], [https://www.ebi.ac.uk/pdbsum/1jw3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jw3 ProSAT], [https://www.topsan.org/Proteins/NESGC/1jw3 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Y1598_METTH Y1598_METTH]] Chaperone or modulator of proteins involved in DNA or RNA processing (Probable).<ref>PMID:15162483</ref> 
[https://www.uniprot.org/uniprot/ARCH_METTH ARCH_METTH] Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity). May also act as a chaperone or modulator of proteins involved in DNA or RNA processing.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jw/1jw3_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jw/1jw3_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jw3 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 1jw3" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Arrowsmith, C H]]
[[Category: Arrowsmith CH]]
[[Category: Chang, X]]
[[Category: Chang X]]
[[Category: Connelly, G]]
[[Category: Connelly G]]
[[Category: Edwards, A M]]
[[Category: Edwards AM]]
[[Category: Kennedy, M A]]
[[Category: Kennedy MA]]
[[Category: Structural genomic]]
[[Category: Yee A]]
[[Category: Yee, A]]
[[Category: Beta-alpha-beta sandwich fold]]
[[Category: Hypothetical protein]]
[[Category: Mth1598]]
[[Category: Nesg]]
[[Category: Ocsp]]
[[Category: PSI, Protein structure initiative]]
[[Category: Unknown function]]

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